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Hair keratins evolved from ancient proteins, diversifying through gene changes, crucial for forming claws and later hair in mammals.

A gene mutation causes early keratinocyte maturation leading to hair loss in Olmsted syndrome.

The document concludes that Hidradenitis suppurativa is often underdiagnosed, lacks definitive treatment, and requires better awareness and management strategies.

Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.

Hairless protein and putrescine regulate each other, affecting hair growth and skin balance.

Boron deficiency in maize affects leaf boron levels and nutrient uptake differently depending on root hair presence and soil type.

Premature graying of hair may suggest health issues and currently lacks effective treatments.

Artemis protein may help control hair growth and health by influencing cell processes.

Keratins are crucial for cell structure, growth, and disease risk.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Antioxidants may help fight oxidative stress linked to autoimmune skin diseases.

Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.

Phosphorylation of certain parts of the PIN3 protein is crucial for its role in plant root growth and response to gravity.

Assessing newborn scalp hair can reveal important health information.

Minoxidil decreases LH expression, while hydralazine has mixed effects on prolyl and lysyl hydroxylase activities.

Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.

The cause of alopecia areata is likely a mix of genetics, immune system issues, and environmental factors, with more research needed to understand it fully.

Wnt7a protein is crucial for development and tissue maintenance and plays varying roles in diseases and potential treatments.

Targeting immune tolerance issues in Alopecia Areata could restore hair growth and maintain remission.

Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.

Targeting the protein Caveolin-1 might help treat a type of scarring hair loss called Frontal Fibrosing Alopecia.

Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.

Genetics, stress, and health issues can cause early hair greying, which affects self-esteem, and there's no cure, only hair dye.

Melanocyte-associated antigens may play a key role in alopecia areata and could be targets for new treatments.

Lupus is a complex disease that requires personalized treatment because it varies greatly between individuals.

The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.

Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.

Atopic dermatitis may have genetic causes and can be treated with pharmacologic methods, glycerin creams, and controlling Staphylococcus aureus colonization.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.