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Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Hirsutism is too much hair growth in women like the pattern in men, often caused by high male hormones, and can be treated with hormone control and hair removal methods.

To diagnose Polycystic Ovarian Syndrome, two out of three signs—irregular periods, high male hormone levels, or cysts on the ovaries—are needed.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Excessive hair growth in women can be harmless or signal serious health issues, and treatment often includes medication and hair removal, with noticeable results after 3-6 months.

The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.

A woman with high testosterone and an adrenal nodule had an ovarian tumor causing her symptoms, which improved after the tumor was removed.

A postmenopausal woman's virilization was caused by a rare ovarian tumor that was hard to detect but was successfully treated with surgery.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

Some conditions mimic PCOS symptoms and need careful diagnosis to treat potentially serious health issues.

Hirsutism in women is often due to hormone sensitivity and has significant psychological effects.

The document concludes that treatments for female hair loss and excessive hair growth are temporary and not well-studied.

Acne and increased body hair in teenage girls are normal but severe cases may need hormone evaluation and treatment can prevent diabetes linked to PCO.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.

Hormones are crucial for regulating body functions and imbalances can lead to health issues.

New signs like changes in blood markers, physical symptoms, and behavioral shifts may help detect hidden steroid use in athletes.

Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.

DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Aging-related hormone changes affect voice quality, especially during puberty, menstruation, pregnancy, and menopause.

The document concludes that personalized hormonal treatments are important for transgender individuals and more research is needed for non-binary treatments.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Androgen therapy might help some women with low libido, but it has risks and should be used carefully.

Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.

A woman's virilization symptoms were caused by her partner's use of testosterone cream, which resolved after they separated.

Gender-affirming hormone treatments need better patient-focused outcome measurements and standardized data collection.

More research is needed to understand how testosterone is maintained in adult males.