![Synthesis of Spiro[cyclohexane-1,2'-[2H]indene] Derivatives as Inhibitors of Steroid 5α-Reductase](/images/research/d91300a7-4d66-4d2c-90ac-293b0dbc5ff5/small/21048.jpg)
research Synthesis of Spiro[cyclohexane-1,2'-[2H]indene] Derivatives as Inhibitors of Steroid 5α-Reductase
Compound 15a was effective in inhibiting 5α-reductase.
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research Commentary on: Hairless and the Polyamine Putrescine Form a Negative Regulatory Loop in the Epidermis
The commentary explains that a balance of HR protein and putrescine is important for normal hair growth.
research The Cutaneous Serotoninergic/Melatoninergic System: Securing a Place Under the Sun
Human skin can make serotonin and melatonin, which help protect and maintain it.
research Melatonin in the Skin: Synthesis, Metabolism, and Functions
Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.
research Protoporphyrin IX: The Good, the Bad, and the Ugly
Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.
research Oxygen, Metabolism, and Regeneration: Lessons from Mice
Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.
research Riboflavin-Responsive Glutaryl CoA Dehydrogenase Deficiency
Taking riboflavin and eating less lysine can help some people with a specific genetic disorder avoid brain damage.
research Fiber-Safe Extraction of Red Mordant Dyes from Hair Fibers
A new method extracts red dyes from wool without damaging it, although it slightly weakens the wool.
research Hair Pigmentation: A Research Update
Hair color is determined by different melanins and changes with age.
research Fiber-Safe Extraction of Red Mordant Dyes from Hair Fibers
Researchers developed a less damaging way to extract red dyes from wool using EDTA and DMF, preserving the fiber's strength for further analysis.
research Efficacy of an Agonist of α-MSH, the Palmitoyl Tetrapeptide-20, in Hair Pigmentation
Palmitoyl tetrapeptide-20 may help reduce hair greying and increase melanin production.
research Recent Advances in Cellulose Nanocrystals-Based Sensors: A Review
Cellulose nanocrystals are promising for making effective, sustainable sensors for various uses.
research Hirsutism: From Brazil to a Place Near You
No treatment fully stops excessive hair growth in women, but various methods can help manage it effectively.
research Monocyclic Aromatic Compounds: Synthesis and Biological Activities
Monocyclic aromatic compounds are important for developing various drugs and treatments.
research Inhibitory Influence of Agmatine on Catamenial-Like Seizure Susceptibility in Progesterone Withdrawn Female Rats
Agmatine may help reduce seizures linked to hormone changes in female rats.
research The Force Is Strong with This One: Metabolism Overpowers Stem Cell Fate
Metabolism plays a key role in determining stem cell fate.
research Protective Role of Melatonin and Its Metabolites in Skin Aging
Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.
research Enzymes
Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
research Bachmann–Bupp Syndrome and Treatment
DFMO treatment improves hair growth, muscle tone, and development in Bachmann-Bupp syndrome patients.
research Taurine, a Non-Proteinous Essential Amino Acid for Human Body Systems: An Overview
Taurine is important for many body functions and its deficiency can cause health problems.
research Ornithine decarboxylase overexpression is a sufficient condition for tumor promotion in mouse skin.
research A Definitive Role of Ornithine Decarboxylase in Photocarcinogenesis
Inhibiting ODC can prevent UV-induced skin cancer.
research Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/– mice
research Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/– mice
research Ornithine Decarboxylase Expression Leads to Translocation and Activation of Protein Kinase CK2 in Vivo
research Ornithine decarboxylase is upregulated by the androgen receptor in skeletal muscle and regulates myoblast proliferation
research Ornithine decarboxylase activity in relation to DNA synthesis in mouse interfollicular epidermis and hair follicles
research Ornithine decarboxylase expression in cutaneous papillomas in SENCAR mice is associated with altered expression of keratins 1 and 10.
research Ornithine Decarboxylase Transgenic Mice as a Model for Human Atrichia with Papular Lesions
ODC transgenic mice can model human hair loss with skin lesions.
research Histidine Decarboxylase Expression Influences the Neofolliculogenesis of Newborn Mouse Dermal Cells
The gene HDC is important for the development of hair follicles in newborn mice.