research Ornithine Decarboxylase Is Upregulated by the Androgen Receptor in Skeletal Muscle and Regulates Myoblast Proliferation
Androgens increase muscle mass by promoting myoblast growth through ornithine decarboxylase.
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30-60 / 459 resultsresearch Heterogeneity of Ornithine Decarboxylase Expression in 12-O-Tetradecanoylphorbol-13-Acetate-Treated Mouse Skin and in Epidermal Tumors
ODC expression in mouse skin and tumors is varied and can be inhibited by retinoic acid or cycloheximide.
research Ornithine Decarboxylase Activity in Relation to DNA Synthesis in Mouse Interfollicular Epidermis and Hair Follicles
research Ornithine Decarboxylase Expression in Cutaneous Papillomas in SENCAR Mice Is Associated with Altered Expression of Keratins 1 and 10
High ODC and low K1 and K10 may indicate early skin tumors in mice.
research Conversion of C57Bl/6 Mice from a Tumor Promotion-Resistant to a Sensitive Phenotype by Enhanced Ornithine Decarboxylase Expression
Increased ornithine decarboxylase makes normally tumor-resistant mice more sensitive to tumors.
research Induction of Ornithine Decarboxylase in Specific Subpopulations of Murine Epidermal Cells Following Multiple Exposures to 12-O-Tetradecanoylphorbol-13-Acetate, Mezerein, and Ethyl Phenylpropriolate
TPA strongly increases ODC activity in certain skin cells, potentially aiding tumor growth.
research Dynamic Expression of Ornithine Decarboxylase in Hair Growth
Ornithine decarboxylase is crucial for hair growth and follicle development.
research Ornithine Decarboxylase Transgenic Mice as a Model for Human Atrichia with Papular Lesions
ODC transgenic mice can model human hair loss with skin lesions.
research A Simple In Vivo System for Studying Epithelialization, Hair Follicle Formation, and Invasion Using Primary Epidermal Cells from Wild-Type and Transgenic Ornithine Decarboxylase-Overexpressing Mouse Skin
Overexpressing ornithine decarboxylase and v-Ha-ras in keratinocytes leads to invasiveness and malignancy.
research Induction of Ornithine Decarboxylase Activity in Hairless Rat Epidermis as a Pharmacological Model: Validation of the Animal Model
Female rats aged 8 weeks are best for this model.
research Antizyme Release Is an Early Event in Ornithine Decarboxylase Induction by Hair Plucking
Hair plucking quickly increases antizyme, reducing a specific enzyme activity in rats.
research Histidine Decarboxylase Expression Influences the Neofolliculogenesis of Newborn Mouse Dermal Cells
The gene HDC is important for the development of hair follicles in newborn mice.
research Epidermal Cell Proliferation and Modulation of the Protective Potency of Dexamethasone Against Phorbol Ester-Induced Ornithine Decarboxylase Activity
Dexamethasone reduces inflammation and delays skin cell changes caused by TPA.
research Conversion of C57Bl/6 Mice from a Tumor Promotion-Resistant to a Sensitive Phenotype by Enhanced Ornithine Decarboxylase Expression
Increased ODC expression makes normally tumor-resistant mice more prone to tumor development.
research Association of a Polymorphism in the Ornithine Decarboxylase Gene with Male Androgenetic Alopecia
research Studies on Enzyme Activities in the Hair Root in Male Pattern Baldness: Glycolytic Enzyme, Acid Hydrolase, Transglutaminase and Ornithine Decarboxylase Activities of Plucked Hair Roots
research Topical Eflornithine: Efficacy in Reducing Unwanted Facial Hair Growth in Women
Eflornithine cream effectively reduces women's unwanted facial hair but hair returns if treatment stops.
research K6/ODC Transgenic Mice as a Sensitive Model for Carcinogen Identification
K6/ODC transgenic mice are effective for quickly identifying cancer-causing chemicals.
research Relation of Skin Polyamines to the Hairless Phenotype in Transgenic Mice Overexpressing Spermidine/Spermine N1-Acetyltransferase
Excessive putrescine causes hair loss in transgenic mice by disrupting hair follicle development.
research Promotion of Skin Carcinogenesis by Dimethylarsinic Acid in Keratin (K6)/ODC Transgenic Mice
Dimethylarsinic acid speeds up skin tumor growth in certain mice.
research Biochemical Analysis of Hair Growth from the Aspects of Aging and Enzyme Activities
Hair regrowth slows with age due to changes in enzyme activity.
research Inhibition of Polyamine Synthesis Alters Hair Follicle Function and Fiber Composition
Polyamines, especially spermidine, are essential for hair growth.
research Tumor Suppressor Activity of ODC Antizyme in MEK-Driven Skin Tumorigenesis
Antizyme slows skin tumor growth by reducing cell growth in mice.
research Vaniqa: Eflornithine 13.9% Cream
Vaniqa cream slows unwanted facial hair growth in women.
research Polyamines and Hair: A Couple in Search of Perfection
Polyamines are important for hair growth, but more research is needed to understand their functions and treatment potential.
research Inhibition of Metastatic Squamous Cell Carcinoma Development in Protein Kinase C Epsilon Transgenic Mice by Alpha-Difluoromethylornithine with Hair Follicle Degeneration and Hair Loss
Alpha-difluoromethylornithine prevents cancer in mice but causes hair loss.
research Regulation Mechanisms of Hair Growth
Hair regrowth slows with age and can be affected by treatments that change enzyme activity in the skin.
research Comprehensive Clinical Management of Hirsutism
New treatments for excessive hair growth in women include insulin modulators and enzyme inhibitors.
research Hairless And The Polyamine Putrescine Form A Negative Regulatory Loop In The Epidermis
Hairless protein and putrescine regulate each other, affecting hair growth and skin balance.
research Topical Spermine And Putrescine Stimulated DNA Synthesis In The Hairless Mouse Epidermis
Topical putrescine and spermine increased DNA synthesis in hairless mouse skin.