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    Glossary Porphyria Cutanea Tarda

    condition causing skin sensitivity to sunlight due to enzyme deficiency

    Porphyria Cutanea Tarda (PCT) is a type of porphyria that affects the skin, causing it to become extremely sensitive to sunlight. This condition leads to blistering, itching, and swelling, primarily on sun-exposed areas. It is caused by a deficiency in the enzyme uroporphyrinogen decarboxylase, which results in the buildup of porphyrins in the skin.

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      research Familial and Sporadic Porphyria Cutanea Tarda

      38 citations , March 2010 in “Medicine”
      In this study, researchers found that hepatitis C virus infection is a significant risk factor for sporadic porphyria cutanea tarda, suggesting familial cases might be more prevalent in areas with low hepatitis C infection rates.

      research Hair darkening in porphyria cutanea tarda

      38 citations , February 2002 in “British journal of dermatology/British journal of dermatology, Supplement”
      This report describes two cases of sustained hair repigmentation related to porphyria cutanea tarda, though the underlying mechanism remains unclear.

      research An epidemic of porphyria cutanea tarda?

      2 citations , February 2000 in “International Journal of Dermatology”
      This article presents four case reports of men with porphyria cutanea tarda and hepatitis C, highlighting associations with polysubstance abuse, primarily alcohol.