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GlossaryPorphyria Cutanea Tarda

condition causing skin sensitivity to sunlight due to enzyme deficiency

Porphyria Cutanea Tarda (PCT) is a type of porphyria that affects the skin, causing it to become extremely sensitive to sunlight. This condition leads to blistering, itching, and swelling, primarily on sun-exposed areas. It is caused by a deficiency in the enzyme uroporphyrinogen decarboxylase, which results in the buildup of porphyrins in the skin.

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research Familial and Sporadic Porphyria Cutanea Tarda

38 citations, March 2010 in “Medicine”

Most patients with Porphyria Cutanea Tarda had skin blisters and were often affected by hepatitis C and alcohol abuse, with differences between familial and sporadic cases.

research Hair Darkening in Porphyria Cutanea Tarda

38 citations, February 2002 in “British journal of dermatology/British journal of dermatology, Supplement”

Two patients with porphyria cutanea tarda experienced their grey hair turning dark again.

research Porphyria Cutanea Tarda in a Patient With Agnogenic Myeloid Metaplasia

5 citations, April 1984 in “Archives of Dermatology”

Porphyria cutanea tarda causes skin issues due to an enzyme deficiency.

research Spironolactone Treatment of Porphyria Cutanea Tarda-Associated Hirsutism

January 1994 in “Journal of Dermatological Treatment”

Spironolactone helped reduce excessive facial hair in a woman with porphyria cutanea tarda.

research 66-Year-Old Woman With Painless Vesicular Lesions

2 citations, July 2009 in “Mayo Clinic Proceedings”

A 66-year-old woman with skin lesions and other symptoms improved after treatment for porphyria cutanea tarda.

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