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The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Male pattern baldness involves genetics, hormones, and needs better treatments.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

The document concludes that rapid identification, isolation, and strict infection control are crucial to manage SARS outbreaks.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Wnt signaling is crucial for skin wound healing and reducing scars.

Certain bacteria and fungi are linked to healthy scalps and dandruff, suggesting that the scalp's microbial balance affects its health.

Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

PRP treatment may stimulate hair growth by promoting blood vessel formation, increasing growth factors, and preventing cell death.

Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.

Older skin has higher cancer risk due to inflammation and stem cell issues.

Injected human hair follicle cells can create new, small hair follicles in skin cultures.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.

Wounds on the face usually heal with scars, but understanding how some wounds heal without scars could lead to better treatments.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.