88 citations,
August 2019 in “Nature communications” Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.
48 citations,
January 2000 in “Hormone Research in Paediatrics” Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.
41 citations,
September 1991 in “Medical hypotheses” Prolactin may be important for skin growth and immune function.
35 citations,
November 2020 in “Dermatologic Therapy” Severe COVID-19 may cause hair loss, and doctors recommend supplements and topical treatments to manage it.
35 citations,
March 2015 in “Experimental Dermatology” Cells from the base of hair follicles help blood vessel cells survive and grow, which is important for healthy hair.
32 citations,
January 2006 in “Acta dermato-venereologica” SACUMAN, a rare condition causing hair loss without clear signs, is often misdiagnosed and needs scalp biopsies for accurate detection.
21 citations,
January 2021 in “Therapeutic Advances in Endocrinology and Metabolism” Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.
20 citations,
November 2019 in “Current Opinion in Systems Biology” The document concludes that computational models are useful for understanding immune responses and could improve cancer immunotherapy.
15 citations,
January 2014 in “BioMed Research International” Heparin and protamine are promising in tissue repair and organ regeneration, including skin and hair.
9 citations,
July 2018 in “European Journal of Dermatology” Brodalumab effectively treated a man's severe hand and foot psoriasis.
5 citations,
June 2018 in “Records of Natural Products” Garden cress extract may help treat skin inflammation and androgen-related disorders.
4 citations,
March 2018 in “Daehan han'yi hag'hoeji/Journal of Korean medicine” Astragalus membranaceus helps regrow hair and reduce hair loss symptoms.
4 citations,
July 2008 in “British journal of dermatology/British journal of dermatology, Supplement” Poor response to topical immunotherapy in alopecia areata patients is linked to impaired cell responses.
3 citations,
January 2023 in “PloS one” Implanting hair-follicle stem cells in mice brains helped repair brain bleeding and reduced brain inflammation.
3 citations,
January 2012 in “Elsevier eBooks” Burn scars form abnormally due to changes in wound healing, and more research is needed to improve treatments.
1 citations,
June 2023 in “Biomolecules & therapeutics” Nitric oxide is important for skin functions and both helps protect against and contributes to skin inflammation and sensitization.
1 citations,
January 2010 in “Elsevier eBooks” Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.
Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.
66 citations,
March 2018 in “British journal of dermatology/British journal of dermatology, Supplement” An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.
50 citations,
March 2021 in “Journal of investigational allergology & clinical immunology” Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.
39 citations,
May 2011 in “Human Immunology” Genetics play a role in acne, but how exactly they contribute is not fully understood.
29 citations,
April 2020 in “Journal of Tissue Engineering and Regenerative Medicine” The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.
29 citations,
March 2020 in “Stem Cell Research & Therapy” Fat stem cells from diabetic mice can help heal skin wounds in other diabetic mice.
28 citations,
November 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” GMG-43AC may help reduce unwanted hair growth and treat certain hair loss conditions.
27 citations,
July 2017 in “European Journal of Dermatology” Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.
26 citations,
April 2019 in “Advances in wound care” Tannic acid helps wounds heal faster in rats by activating certain cell signals and reducing inflammation.
23 citations,
January 2016 in “Frontiers in immunology” Using low-dose IL-2 to increase regulatory T cells might be a safe way to treat type 1 diabetes without severe side effects.
22 citations,
March 2017 in “Scientific reports” Double-stranded RNA causes inflammation in hair follicle cells, which may help understand and treat alopecia areata.
20 citations,
December 2013 in “Journal of Dermatology” UV-B light increases inflammation-related substances in acne-related skin cells.
19 citations,
February 2008 in “Archives of Dermatological Research” Mast cells might contribute to hair loss by causing skin thickening.