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A woman developed severe kidney injury from using simvastatin with ciclosporin, highlighting the need for careful monitoring when combining these drugs.

Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.

The medication lopinavir-ritonavir may cause severe hair loss.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

Finasteride effectively treats male pattern baldness, improving hair growth and density.

Gefitinib can cause skin problems, diarrhea, and nausea, but rarely causes severe lung disease or hair loss.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.

Subcutaneous contraceptives can cause side effects like menstrual changes, headaches, weight gain, and pain at the implant site.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.

Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.

Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.

Finasteride helps hair growth but may cause sexual side effects and depression.

Treating epilepsy is complex, requiring careful drug choice and patient adherence to manage seizures and side effects.

Retinoids are effective for skin conditions like severe acne and psoriasis but must be used with caution due to potential side effects and risks during pregnancy.

Certain medications can reduce mortality risk in COPD patients, but others can increase risks of cardiovascular issues, postoperative delirium, and other adverse effects.

Taking Dutasteride with Ketoconazole can increase Dutasteride's effects and side effects.

Some skin medications can have harmful interactions with the COVID-19 drug nirmatrelvir-ritonavir, but not with molnupiravir.

Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.

Origanum vulgare leaf extract reduces liver and kidney damage caused by finasteride in mice.

Food intake, not genetics, affects how the body processes tadalafil and finasteride.

The document explains how the immune system reacts to organ transplants and the treatments used to prevent rejection.

Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.

Psychotropic medications can cause skin problems, including serious conditions, and patients should be monitored closely.

Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.

Scientists improved an enzyme to better produce a hair growth-promoting chemical from an immunosuppressant.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The decision tree can predict drug absorption issues with good accuracy but needs more validation and adjustments for other factors.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.