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    Glossary CXXC5

    protein involved in inhibiting hair follicle regeneration

    CXXC5 is a protein that plays a role in regulating hair growth and development. It acts as a negative regulator in the Wnt signaling pathway, which is crucial for hair follicle regeneration. Inhibiting CXXC5 has been studied as a potential treatment for conditions like alopecia, where hair loss occurs.

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    Research 30 of 76

    1. Targeting of CXXC5 by a Competing Peptide Stimulates Hair Regrowth and Wound-Induced Hair Neogenesis Journal of Investigative Dermatology · 2017 · 37 citations
    2. CXXC5: A novel regulator and coordinator of TGF-β, BMP and Wnt signaling Journal of Cellular and Molecular Medicine · 2018 · 28 citations
    3. Inhibiting the cytosolic function of CXXC5 accelerates diabetic wound healing by enhancing angiogenesis and skin repair Experimental & Molecular Medicine · 2023 · 19 citations
    4. The Negative Regulator CXXC5: Making WNT Look a Little Less Dishevelled Journal of Investigative Dermatology · 2017 · 8 citations
    5. Signal integrator function of CXXC5 in Cancer Cell Communication and Signaling · 2025
    6. CXXC5 Mediates DHT-Induced Androgenetic Alopecia via PGD2 Cells · 2023
    7. Novel small molecules downregulate CDK1 expression and inhibit Wnt/β-catenin signaling in cutaneous squamous cell carcinoma by targeting its distinct tumor-specific cellular landscape Experimental & Molecular Medicine · 2025
    8. Pathogenic Mechanisms and Mechanism‐Directed Therapies for Androgenetic Alopecia: Current Understanding and Future Directions Dermatologic Therapy · 2025
    9. Effect of DNA aptamer through blocking of negative regulation of Wnt/β‐catenin signaling in human hair follicle dermal papilla cells Skin research and technology · 2023
    10. Wnt/β-Catenin Signaling Pathway Targeting Androgenetic Alopecia: How Far Can We Go Beyond Minoxidil and Finasteride? Journal of Medicinal Chemistry · 2025
    11. Structures of Get3d reveal a distinct architecture associated with the emergence of photosynthesis Journal of Biological Chemistry · 2023
    12. Getting to the Core of the Dermal Papilla Journal of Investigative Dermatology · 2017 · 21 citations
    13. KY19382, a novel activator of Wnt/β‐catenin signalling, promotes hair regrowth and hair follicle neogenesis British Journal of Pharmacology · 2021 · 13 citations
    14. Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds Nature Communications · 2019 · 301 citations
    15. Review of Hair Follicle Dermal Papilla cells as <i>in vitro</i> screening model for hair growth International Journal of Cosmetic Science · 2018 · 76 citations
    16. Transcutaneous implantation of valproic acid-encapsulated dissolving microneedles induces hair regrowth Biomaterials · 2018 · 68 citations
    17. Androgen modulation of Wnt/β-catenin signaling in androgenetic alopecia Archives of Dermatological Research · 2018 · 39 citations
    18. Chitosan/LiCl composite scaffolds promote skin regeneration in full-thickness loss Science China Life Sciences · 2019 · 24 citations
    19. Androgenetic alopecia: combing the hair follicle signaling pathways for new therapeutic targets and more effective treatment options Expert Opinion on Therapeutic Targets · 2019 · 19 citations
    20. Insights into the regeneration of skin from <i>Acomys</i> , the spiny mouse Experimental Dermatology · 2018 · 19 citations
    21. Epidermal Stem Cells in Hair Follicle Cycling and Skin Regeneration: A View From the Perspective of Inflammation Frontiers in Cell and Developmental Biology · 2020 · 18 citations
    22. Lifestyle factors affecting the pathogenesis of androgenetic alopecia: a literature review Frontiers in Public Health · 2026
    23. Lgr5 Stem Cells and Potential Treatments for Hair Loss Theoretical and Natural Science · 2026
    24. Dermal niche signaling and epidermal stem cells Advances in stem cells and their niches · 2019
    25. Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease Genes & Development · 2008 · 667 citations
    26. Roles of <i>jumonji</i> and <i>jumonji</i> family genes in chromatin regulation and development Developmental Dynamics · 2006 · 178 citations
    27. Characterization of Novel Cutaneous Human Papillomavirus Genotypes HPV-150 and HPV-151 PLoS ONE · 2011 · 20 citations
    28. Hair growth promotion by Necrostatin-1s Scientific Reports · 2020 · 12 citations
    29. KY19382 Accelerates Cutaneous Wound Healing via Activation of the Wnt/β-Catenin Signaling Pathway International Journal of Molecular Sciences · 2023 · 18 citations
    30. Pyruvate Kinase M2 Accelerates Cutaneous Wound Healing via Glycolysis and Wnt/β-Catenin Signaling Pharmaceutics · 2023 · 10 citations