42 citations
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July 2015 in “Journal of The American Academy of Dermatology” This review discusses diagnostic and treatment considerations for women with cutaneous hyperandrogenism, noting therapeutic options are more effective for hirsutism and acne than for androgenetic alopecia, but reports no new clinical results.
3 citations
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November 2013 in “PubMed” 
2 citations
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January 2014 in “Advanced Biomedical Research” This article describes SAHA syndrome, which includes symptoms of nodulocystic or severe acne, female pattern hair loss, and hirsutism, but reports no new results.
This study found that cyproterone compound is not more effective than oral isotretinoin in treating nodulocystic acne in adult females with SAHA syndrome or cutaneous hyperandrogenism, suggesting isotretinoin may be preferable due to its established effectiveness in reducing acne lesions.
December 2023 in “Expert Review of Endocrinology & Metabolism” In this study, researchers described hyperandrogenism as a condition resulting from excessive androgen production, which can lead to symptoms like acne, hirsutism, and hair loss, particularly relevant for dermatological evaluation and management in adult females.
January 2020 in “Medical journal of Dr. D.Y. Patil Vidyapeeth” This study found that polycystic ovarian syndrome (PCOS) is the most common cause of cutaneous manifestations of hyperandrogenism in women of reproductive age, with hirsutism severity correlated to serum testosterone levels.
22 citations
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January 2002 in “Treatments in endocrinology” This review examines the role of androgens in cutaneous disorders and the potential therapeutic effects of different oral contraceptives, noting variations in individual responses and the influence of genetic and local factors but reports no new clinical results.
5 citations
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December 2004 in “Dermatology” This review describes two cases of young women with primary amenorrhea and hyperandrogenemia, suggesting that adrenal tumors should be considered in patients with significantly elevated circulating testosterone levels.
17 citations
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April 2010 in “Archives of Gynecology and Obstetrics” This study found that obese Taiwanese women had a lower incidence of acne than non-obese women, despite having higher serum testosterone levels.
September 2016 in “Gynecology Obstetrics and Reproductive Medicine” This review outlines the diagnostic criteria and management strategies for polycystic ovary syndrome, focusing on hyperandrogenism's cutaneous manifestations, such as hirsutism and acne, and describes treatments like oral contraceptives and antiandrogens to address these issues.
53 citations
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December 2015 in “JAMA Dermatology” This study found that hirsutism and acanthosis nigricans are the most reliable skin markers for diagnosing polycystic ovary syndrome in women and suggest a need for further evaluation of possible metabolic issues.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this cross-sectional study at a tertiary care hospital, researchers found a significant correlation between cutaneous manifestations like hirsutism and acne and biochemical hyperandrogenism levels in women with PCOS, suggesting these skin conditions can predict elevated androgen levels.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that hirsutism and acne are strong predictors of biochemical hyperandrogenism in women with polycystic ovary syndrome.
April 2016 in “Journal of The American Academy of Dermatology” This study reported that inpatient dermatology consultations at a large tertiary care center led to treatment changes in 81.9% of cases, particularly improving management of complex cutaneous conditions associated with systemic diseases.
April 2016 in “Journal of The American Academy of Dermatology” This study found that dermatology consultations in a tertiary care center led to treatment changes in most cases, especially for complex conditions potentially linked to systemic disease.
April 2016 in “Journal of The American Academy of Dermatology” This study found that dermatology consultations in a tertiary care center often led to treatment changes, particularly for complex dermatologic conditions potentially linked to systemic disease.
This study reported that women with acanthosis nigricans and insulin resistance often exhibit signs of hyperandrogenism, including hirsutism, and have elevated fasting plasma insulin compared to controls.
233 citations
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November 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” This review explores androgen metabolism in the skin, highlighting enzyme localization and potential implications for treating androgen-dependent skin conditions, but it reports no new clinical results.
16 citations
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March 2014 in “Journal of the European Academy of Dermatology and Venereology” This study found that acne was the most common dermatological manifestation in Korean women with polycystic ovary syndrome, particularly those with a specific combination of symptoms, showing distinct variations in serum hormonal and metabolic parameters.
5 citations
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March 2020 in “Current Opinion in Endocrine and Metabolic Research” This review discusses the contribution of non-androgen causes to acne and female pattern hair loss in PCOS and emphasizes the need for targeted treatment approaches without relying on hyperandrogenism as a diagnostic marker.
December 2025 in “BENTHAM SCIENCE PUBLISHERS eBooks” This review discusses the interplay between endocrinology and dermatology in PCOS, highlighting the roles of hyperandrogenism, insulin resistance, and chronic inflammation in related skin conditions, but reports no new clinical results.
November 1993 in “PubMed” This article reviews the role of androgens in skin metabolism and diseases like acne and androgenic alopecia, but reports no new clinical results; the authors note unresolved issues regarding androgen interactions in skin structures.
March 2025 in “Annals of Medicine and Surgery” This review discusses the pathophysiology, diagnosis, management, and psychosocial impact of skin manifestations in PCOS and emphasizes the need for holistic, personalized care without reporting new results.
This study found that expert consensus endorsed myo-inositol, alone or combined with folic acid and vitamin D₃, as an effective, well-tolerated option for managing acne and hirsutism in PCOS.
This study found that cutaneous manifestations such as hirsutism, acne, and acanthosis nigricans in women with PCOS correlate significantly with hormonal imbalances and insulin resistance.
July 2019 in “International Journal of Research in Dermatology” In this study, acne vulgaris was identified as the most common skin condition among women with polycystic ovary syndrome, notably affecting the 21-25 age group.
2 citations
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June 2017 in “Journal of The American Academy of Dermatology” This article discusses the uncertainty regarding distinct skin findings and cardiometabolic profiles among PCOS subtypes and reports no new clinical data.
May 2026 in “Endocrine Connections” This review posits that alopecia in PCOS results from the interaction between local follicular signaling failures, insulin resistance, inflammation, and genetic predispositions, rather than solely from androgen excess, and recommends a systems-level framework for its management.
43 citations
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May 1988 in “British Journal of Dermatology” This study reported that patients with acanthosis nigricans and insulin resistance exhibited higher insulin levels and were associated with increased insulin resistance correlating with serum testosterone levels.
97 citations
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March 2009 in “Dermato-endocrinology” This review explores the role of hormones in pilosebaceous units and associated skin disorders, focusing on androgen action, without presenting new clinical findings.