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Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Different types of stem cells and their environments are key to skin repair and maintenance.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Finasteride effectively treats baldness but may cause sexual side effects.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Liposomes could improve how skin care products work but are costly and not very stable.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

People with alopecia areata often have other health issues like skin diseases, metabolic syndrome, stomach infections, lupus, anemia, thyroid problems, mental health issues, vitamin D deficiency, and hearing and eye problems.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.

Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Hormones and genetics affect hair growth and patterns, with some changes reversible and others not.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Prolactin slows down hair growth in mice.