14 citations
,
January 2006 in “Skinmed” A woman developed white patches on her skin and curly hair after hepatitis C treatment, likely due to the medication interferon alpha.
7 citations
,
August 2018 in “Journal of cosmetic dermatology” This study found that chemical hair straightening significantly reduced hair curl and improved smoothness and shine, but did not significantly affect transverse fissures or split ends, indicating potential benefits with some side effects.
7 citations
,
January 2012 in “International Journal of Trichology” A man with Woolly Hair Syndrome had very curly, fragile hair, and doctors used a special scalp examination to diagnose him without invasive tests.
August 2024 in “International Journal of Dermatology” This study, published in the September issue of the Journal, explores challenges and treatments for curly-textured hair, investigating glucagon-like peptide-1 agonists' impact on hair loss and discussing a promising therapy using adipose stem cell-derived exosomes to promote hair growth.
January 2022 in “Surgical & Cosmetic Dermatology” This case report described a rare instance of new curly hair growth in a patient undergoing isotretinoin treatment for acne vulgaris, highlighting the potential for isotretinoin to alter hair fiber curvature.
May 2015 in “Journal of The American Academy of Dermatology” A woman with Parry-Romberg syndrome developed new curly hair on one side of her scalp, a condition not previously linked to the syndrome.
January 2009 in “Nihon Keshouhin Gijutsushakaishi/Journal of S C C./Nihon Keshouhin Gijutsushakai kaishi” This study found that the structural and chemical composition of human curly hair may resemble that of sheep wool, implying a shared characteristic among mammals with wavy hair.
6 citations
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December 2011 in “Clinical and Experimental Dermatology” A woman developed rare, unexplained curly hair on her scalp and eyelashes.
September 2021 in “CRC Press eBooks” This article discusses the characteristics and pathogenesis of acne keloidalis nuchae among men with coarse curly hair, reviewing its association with factors like chronic inflammation and potential roles for metabolic syndrome and infection. It reports no new results.
7 citations
,
September 2006 in “Molecular Carcinogenesis” This study observed that K5Cre +/+ transgenic mice develop a distinct phenotype characterized by wavy hair, curly whiskers, and an increased rate of papilloma malignant transformation.
5 citations
,
March 2017 in “Gene” This study found that the transcription factor CAP1 negatively regulates KRT83 expression in Tan sheep, possibly influencing their curly hair phenotype.
2 citations
,
March 2010 in “European journal of dermatology/EJD. European journal of dermatology” This case report describes a 5-year-old girl with trichorrhexis nodosa and highlights the presence of isolated curly hairs on her scalp despite hair loss over four months.
35 citations
,
November 2021 in “Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology” This study identified dynamic changes in DNA methylation associated with different growth stages in Tan sheep, which may offer insights to retain their valuable curly fleece as they age.
34 citations
,
August 2002 in “British Journal of Dermatology” This study observed that two patients treated with interferon α-2b and ribavirin for chronic hepatitis C experienced complete and reversible straightening of their natural curly hair, which recurred with treatment resumption.
18 citations
,
March 1992 in “Archives of Dermatology” This case report presents a 28-year-old man with scarring alopecia unresponsive to topical treatments, alongside a family history of keratosis pilaris and unique curly scalp hair.
In this summary, the researchers describe the Brazilian keratin treatment as a popular hair-straightening process that originated in Brazil in 2003 and has since gained global traction, particularly for smoothing and straightening curly or frizzy hair through a keratin-based product and heat application.
January 2026 in “Dermatology Research and Practice” In this cross-sectional study of Saudi Arabian citizens, researchers found that increased frequency of shampooing improved the condition of both hair and scalp, with long and curly hairstyles being more prone to breakage and daily hair loss.
September 2025 in “Indian Journal of Dermatology” In this case report, researchers detailed a 22-year-old Turkish woman diagnosed with autosomal recessive woolly hair/hypotrichosis (ARWH/H), linked to a mutation in the LIPH gene, resulting in sparse, poorly growing, curly hair, highlighting the need for genetic consideration in similar hair conditions.
February 2025 in “International Journal of Cosmetic Science” This study found that treating hair with ATS, formed from fumaric acid and cysteamine, effectively improved hair quality by increasing moisture content and altering the internal structure of strong curls.
This article reviews a clinical case of pseudofolliculitis, highlighting its chronic nature, commonality in individuals with curly hair, and suggests management strategies, but reports no new clinical results.
April 2020 in “International Journal of Cosmetic Science” This study found that improved protein extraction methods enhanced the resolution of hair proteins on gels, but differences in protein abundance between curly and straight Japanese women’s hair were minimal and unlikely to affect hair structure.
7 citations
,
January 2013 in “Indian Journal of Plastic Surgery” This study found that beard and body hair can be used as additional donor sources for scalp transplants in androgenic alopecia, retaining their original color, curl, and calibre.
3 citations
,
January 2002 in “Springer eBooks” This study found that using cationic and non-ionic polymers during alkaline hair relaxer treatments may help strengthen hair and control swelling, potentially reducing damage.
July 2024 in “Journal Archives of Health” This study reviewed the medical literature on generalized woolly hair and reported that while there are no effective treatments, some narratives suggest that topical Minoxidil may help with hypotrichosis associated with the condition.
40 citations
,
June 2013 in “Journal of cosmetic dermatology” This review discusses the widespread use of Brazilian keratin treatments and notes that many contain formaldehyde, marketed as safe despite potential safety concerns, but reports no new clinical results.
In this review of permanent hairstyles like perms, the authors discuss the chemical processes involved and highlight potential risks such as hair and scalp damage, emphasizing the need for careful client assessment and safe application techniques to mitigate these risks.
September 2019 in “University of the Arts London Research Online (University of the Arts London)” This study tested the effects of protective pre-treatments on African hair and found that these treatments, combined with moderate grooming, may help maintain cuticle integrity.
252 citations
,
November 1995 in “The EMBO Journal” Blocking EGFR in mice causes hair loss and skin changes.
109 citations
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June 2000 in “Development” This study reports that activating Notch signaling in the hair follicle cortex of transgenic mice caused abnormal differentiation of the medulla and cuticle, highlighting potential cell-cell interactions.
26 citations
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October 1999 in “Archives of Dermatology” This discussion suggests that acquired progressive kinking of hair in androgen-dependent scalp areas may indicate the early stages of androgenetic alopecia with a poor prognosis, but it offers no new clinical findings.