Acquired Progressive Kinking of the Hair

October 1999 in “ Archives of Dermatology ”

Antonellá Tosti, Bianca Maria Piraccini, Massimiliano Pazzaglia, Cosimo Misciali

acquired progressive kinking androgenetic alopecia androgen-dependent areas scalp hair hair curling male pattern baldness

TLDR Curly hair in certain scalp areas can be an early sign of hair loss.

The study focused on 7 male patients aged 15 to 22 with acquired progressive kinking of the hair (APKH), which presented as curly, frizzy, and lusterless hair in the frontotemporal region and progressed to androgenetic alopecia over an average of 4.5 years. All patients had a strong family history of androgenetic alopecia, and scalp pathology indicated early stages of this condition. Treatment with topical minoxidil did not prevent hair thinning, suggesting a poor prognosis for APKH as it appeared to be an early form of androgenetic alopecia. The study emphasized the need for further research into the causes and treatment of APKH, as existing treatments were largely ineffective.

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Research cited in this study

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research Acquired Progressive Kinking of the Hair in a Prepubertal Boy

10 citations , November 1997 in “British Journal of Dermatology”

A 10-year-old boy had the earliest reported case of hair that became progressively kinkier but eventually returned to normal on its own.

Increased Scalp Skin and Serum 5a-Reductase Reduced Androgens in a Man Relevant to the Acquired Progressive Kinky Hair Disorder and Developing Androgenetic Alopecia

research Increased Scalp Skin and Serum 5a-Reductase Reduced Androgens in a Man Relevant to the Acquired Progressive Kinky Hair Disorder and Developing Androgenetic Alopecia

11 citations , September 1997 in “Archives of Dermatology”

Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.

research Diagnostic and Predictive Value of Horizontal Sections of Scalp Biopsy Specimens in Male Pattern Androgenetic Alopecia

309 citations , May 1993 in “Journal of The American Academy of Dermatology”

Horizontal scalp biopsy sections effectively diagnose and predict MPAA, with follicular density and inflammation impacting hair regrowth.

research Acquired Progressive Kinking of Hair

33 citations , August 1985 in “Archives of Dermatology”

Acquired Progressive Kinking of Hair is likely an early sign of male pattern baldness.

research Whisker Hair: An Update

6 citations , June 1981 in “PubMed”

Whisker hair in young people might predict severe future hair loss.

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