Generalized Woolly Hair: Case Report and Literature Review

Woolly hair is a rare congenital scalp disorder characterized by excessively curly hair with a medium amplitude of up to 0.5 cm and an incomplete anagen phase, resulting in shorter hair. It can be classified into four types and may indicate a systemic comorbidity, known as woolly hair syndrome, or appear as non-syndromic woolly hair. The condition, first described in a European family in 1907, is now most commonly associated with the Japanese population, linked to autosomal recessive or dominant genetic mutations, particularly in genes with compound heterozygous variants. Current studies indicate no effective treatments for this condition, although some narratives suggest that topical Minoxidil may help with hypotrichosis.