Adverse Reaction to Isotretinoin: Alteration of the Hair Shaft Structure

January 2022 in “ Surgical & Cosmetic Dermatology ”

Rodrigo Lousada, Edilbert Pellegrini Nahn-Júnior, Hudson Dutra Rezende, Liana Moura de Almeida, Ana Paula Moura de Almeida, Maria Fernanda Reis Gavazzoni Dias

isotretinoin acne vulgaris oral retinoids hair texture hair shaft structure hair fiber curvature Accutane

TLDR Isotretinoin can rarely cause hair to grow curly.

The document reported a rare case of a patient treated with isotretinoin for acne vulgaris who experienced changes in hair texture, specifically new growing curly hair. While changes in hair shape, color, and texture were known to occur during therapy with oral retinoids, modifications in hair fiber curvature induced by isotretinoin were extremely rare.

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research Adverse Effects of Isotretinoin: A Retrospective Review of 1743 Patients

121 citations , June 2010 in “Australasian Journal of Dermatology”

Most people on isotretinoin had chapped lips, but only a few stopped the medicine due to side effects.