Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that using a novel dissolving microneedle with valproic acid effectively enhances hair follicle regrowth through improved delivery and activation of the Wnt/β-catenin pathway compared to topical application.

This article details laboratory methods for isolating and culturing human dermal papilla cells but provides no new experimental results.

New methods for growing skin cells can improve skin grafts by building blood vessels within them.

This review suggests that omitting the proteolysis step and including tissue pieces in mesenchymal stem cell isolation may improve cell quality, reduce contamination risk, and lower costs and processing time in clinical applications.

This study introduced a new classification system for distinguishing between anagen VI and early catagen stages in human hair follicle organ culture, using it to confirm eflornithine's ability to induce premature catagen.

In this study, researchers developed a simple, non-invasive method to monitor circadian gene expression using whole hair root cultures, finding that elderly dementia patients' peripheral clocks still oscillate similarly to younger, healthier individuals, which suggests cellular senescence minimally affects some aspects of circadian rhythms.

This study found that expanding hair follicle keratinocytes with a fibroblast feeder followed by short-term coculture with dermal papilla cells could restore their ability to form new hair follicles.

In this study, mouse hair follicle stem cells cultured in mouse embryonic fibroblast/keratinocyte serum-free medium exhibited the highest proliferative ability and stronger osteogenic differentiation potential, similar to hair follicle dermal papilla cells.

This study describes a simplified method for isolating and cultivating human hair follicle papillae that can be easily executed by new lab personnel.

In this study, the researchers optimized a method for culturing melanocyte precursors from hair follicles and found that 1,25-dihydroxyvitamin D3 significantly promotes their differentiation and melanin synthesis.

The researchers reported that human foreskin fibroblasts isolated by enzyme digestion method proliferated faster and were purified more quickly than those isolated by the inverted tissue culture method; additionally, post-psoralen photoactivation therapy moderately repaired UVB-induced damage in these fibroblasts, suggesting potential clinical applications.

This study established an optimal in vitro culture system for fine-wool sheep hair follicle stem cells, finding a combination of two-step enzymatic digestion and mechanical separation to be the most effective method.

This study supports that an antibody response against anagen-specific hair follicle antigens, including trichohyalin and keratin 16, may play a role in alopecia areata.

This study successfully optimized a culture strategy for dermal papilla cells and established an immortalized cell strain, iDP6, which closely resembles primary DP cells in key characteristics.

This study reported that gain-of-function mutations in TRPV3 lead to hair loss in mice by disrupting inner root sheath keratinocyte differentiation, ultimately causing follicular keratinocyte stem cell exhaustion and permanent follicle disruption.

This study successfully developed a method to culture human hair follicle cells without a biological feeder layer, maintaining cell differentiation for a month.

This review discusses methods for evaluating hair growth-promoting effects of candidate substances for androgenetic alopecia, focusing on cell assays, organ cultures, and animal models, and reports no new results.

This study reviewed various methods and techniques aimed at overcoming limitations in culturing human hair follicles, specifically focusing on restoring the inductivity of hair follicle cells for successful hair regeneration.

This research concluded that the novel hydrogel PlacMA, derived from human placenta and curable by visible light, shows promise for cell culture and tissue engineering applications due to its tunable properties.

This review study focused on various in vitro methods to evaluate skin permeation and retention of sunscreens, highlighting the importance of assessing sunscreen penetration due to widespread nanomaterial usage and advancements in cosmetic formulation.

This review covers potential molecular targets for androgenetic alopecia treatments but presents no new experimental findings; the authors highlight various in vitro and in vivo screening methods for therapeutic compounds.

This review discusses the biology and signaling mechanisms of dermal papilla cells in hair follicle growth and reports no new clinical results; the authors emphasize the importance of optimizing culture conditions for hair restoration.

This study introduced a simple and reliable in vitro assay capable of large-scale simultaneous screening of hair growth-promoting compounds using a 3D co-culture system of human dermal papilla and outer root sheath cells.

Hair disease research is a growing and evolving field in dermatology, with recent significant advances.

This review discusses current experimental approaches for regenerating human hair follicles using tissue engineering and isolated cells, but reports no successful strategies with adult cells yet found.

This review discusses dermatophytosis in equines, caused primarily by T. equinum, noting its global prevalence and highlighting diagnostic methods; it reports no new clinical results.

This review discusses strategies to enhance mesenchymal stem cell therapy effectiveness but reports no new clinical results; it highlights the need for improved consistency and efficacy in MSC-based treatments.

This study found that the human placenta extracellular matrix hydrogel restored the hair-inductive capacity of high-passaged dermal papilla cells, enabling them to regenerate new hair follicles when co-grafted with mouse epidermal cells.

In this review, researchers summarize key factors in constructing skin organoids, including cell source and assembly methods, and emphasize advances such as air-liquid interface culture for improving tissue development, aiming to guide standardized protocols and future clinical applications.