1 citations
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January 2022 in “The Egyptian Journal of Hospital Medicine ” This study found that both superficial cryotherapy and intralesional corticosteroid injections significantly improved hair growth in patients with alopecia areata, with similar efficacy between the two treatments, establishing cryotherapy as a simple and noninvasive treatment option.
1 citations
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January 2013 in “Archives of Aesthetic Plastic Surgery” This study found that combining liposuction with diode laser ablation was effective in treating axillary osmidrosis, with high patient satisfaction and no significant complications reported over a 10-month follow-up period.
In this case series, researchers reported an unexpectedly rapid and positive response to a topical, hydrogel-based botanical treatment for androgenetic alopecia in both male and female volunteers, achieving significant improvement in hair loss within 90 days instead of the planned 270 days.
March 2026 in “Frontiers in Immunology” In this study, a 49-year-old female with metastatic adrenocortical carcinoma experienced an abscopal effect following pulse electric field ablation, suggesting potential as an adjunct to systemic immunotherapy for liver tumors.
29 citations
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June 2018 in “Scientific Reports” In this study, Alox15 knockout mice exhibited disrupted skin integrity and increased inflammation, suggesting that Alox15-mediated resolvin D2 production is crucial for maintaining skin homeostasis by suppressing inflammation.
15 citations
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January 2018 in “Acta dermato-venereologica” This study found that dermatological treatments significantly reduce health-related quality of life among patients with various skin conditions, suggesting that the burden of these therapies should be considered in treatment planning and development.
9 citations
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July 2011 in “The Journal of Sexual Medicine” This article examines 5 alpha-reductase inhibitors and their link to persistent sexual dysfunction, but it reports no new clinical findings.
3 citations
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August 2017 in “Oral and Maxillofacial Surgery Cases” This study observed complete resolution of neuropathic pain symptoms in a patient after a fat grafting PRP procedure, suggesting it may be a less invasive treatment alternative.
2 citations
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January 2015 in “Case reports in neurological medicine” In this case report, pulsed radiofrequency neuromodulation provided over 80% pain relief for five months in a patient with chronic lesser occipital nerve pain after other treatments failed.
1 citations
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January 2019 in “Springer eBooks” Hidradenitis Suppurativa is a chronic skin condition best treated early with surgery for better outcomes and less recurrence.
1 citations
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January 2001 in “Dermatologic Surgery” Pulsed dye laser and hydrogel dressings effectively treat hypertrophic scars.
January 2022 in “Dermatology Review” In this study, microneedling combined with bleomycin treatment for plantar warts improved the response time and reduced the number of treatment sessions needed, with a relapse rate similar to other injection-based methods.
January 2001 in “Dermatologic Surgery” The letters discussed medical tools, costs, treatment efficacy, and patient care complexities.
January 1989 in “Side effects of drugs annual” This chapter reviews studies on the side effects of cytostatics and immunosuppressive drugs, detailing various toxicities such as cardiovascular, pulmonary, and neurotoxicity, but provides no new clinical results.
53 citations
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June 1982 in “The BMJ” Cooling the scalp below 22°C before and during chemotherapy can help prevent hair loss.
This study tested a novel cryo-carboxy dispensing device for treating androgenetic alopecia in six volunteers and found an unexpectedly rapid and positive response, with significant hair regrowth observed by day 90, prompting early conclusion of the trial.
March 2026 in “Al-Azhar International Medical Journal /Al-Azhar International Medical Journal” In this study, patients with resistant alopecia areata treated with 35% trichloroacetic acid showed significantly better outcomes compared to those receiving superficial cryotherapy, with TCA demonstrating "excellent" results in 37.5% of cases versus 6.25% for cryotherapy.
70 citations
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June 2017 in “Nature Communications” This study introduced a new technique, 2Phatal, enabling precise apoptotic cell ablation in living animals, revealing unique cell-type differences in apoptosis-related dynamics.
April 2023 in “Journal of Investigative Dermatology” This review found that while about 60% of patients with alopecia areata responded to liquid nitrogen cryotherapy in existing studies, no significant efficacy difference was observed compared to intralesional steroid injections, though relapse rates may be lower with cryotherapy.
1 citations
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August 2021 in “Journal of The American Academy of Dermatology” This study investigates the effects of ice cooling and vibration on reducing pain during platelet-rich plasma injections for alopecia, especially due to concerns about lidocaine reducing PRP efficacy.
7 citations
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December 2020 in “ACS biomaterials science & engineering” In this study, researchers demonstrated that human hair keratins can self-assemble into stable nanofibrous networks in vitro, which are compatible with human skin cells and useful for regenerative applications.
January 2016 in “Springer eBooks” New materials and methods could improve skin healing and reduce scarring.
April 2021 in “Sohag Medical Journal” This research suggests that superficial cryotherapy is a safe and nearly as effective alternative to topical steroids and PUVA therapy for treating alopecia areata, especially in children.
39 citations
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January 1994 in “European Journal of Cancer” In this study, scalp hypothermia with the Theracool™ cooling machine was largely ineffective for preventing alopecia in breast cancer patients undergoing a chemotherapeutic regimen including cyclophosphamide and anthracyclines.
2 citations
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January 2023 in “Biomedicines” This study found that using a combination of ablative CO₂ fractional laser and fetal fibroblast transplantation significantly reduced scarring in mice, with long-term sphere-forming cultured fibroblasts producing scar appearances closest to normal skin.
16 citations
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October 2016 in “The Journal of Dermatology” In this retrospective study, 60.9% of patients with alopecia areata responded to superficial hypothermic cryotherapy, with effectiveness notably higher when the treatment interval was 2 weeks or less, particularly in early disease stages, and minimal side effects were observed.
23 citations
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March 1998 in “Dermatologic Surgery” This narrative discusses the use of radiosurgery in cosmetic procedures and reports no new clinical results.
May 2025 in “Drug Delivery and Translational Research”
December 2024 in “Acta Medica” In this case report, a patient developed facial zona zoster as an unexpected complication following cryotherapy, adding to the list of known adverse effects such as dyspigmentation, scar formation, and hair loss.
69 citations
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August 1995 in “Annals of Plastic Surgery” This study showed that ultrapulse carbon dioxide laser ablation can precisely remove rabbit skin without scarring, facilitating normal skin and hair restoration within one month.