31 citations
,
December 2021 in “Materials” In a study using a mouse model of diabetes, chitosan-based hydrogels increased healing markers and improved wound closure and tissue repair compared to untreated wounds, but human efficacy needs further validation.
7 citations
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May 2024 in “Gels” This study evaluated a new collagen and tannic acid hydrogel in rat liver and heart bleeding models, finding it reduced blood loss and hemostatic time compared to commercial products, with benefits such as enhanced biodegradability and potential for clinical use.
1 citations
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November 2025 in “Molecules” This review highlights the potential of ellagic acid for treating various skin conditions due to its antioxidant, anti-inflammatory, and depigmenting properties, but notes that novel formulations are needed to overcome its poor solubility and skin permeability to enhance clinical efficacy.
December 2025 in “Cosmetics” In a laboratory study, researchers found that a novel Bioactive Crosslink Repair Complex improved both the protection and repair of chemically damaged hair, enhancing tensile strength, shine, and cuticle alignment when added to bleaching mixtures and leave-in conditioners.
February 2025 in “Processes” This study highlights the potential of chitosan nanoparticles to improve cannabidiol solubility and delivery for treating alopecia, suggesting a promising approach for transdermal delivery of hydrophobic compounds.
1 citations
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February 2023 in “Applied sciences” This study found that methylcellulose-based hydrogels can effectively deliver growth hormone through the skin, with albumin increasing the hormone's permeation to 93% in simulated in vivo conditions.
This review found that exposure to pollutants like PM, NOx, and PAHs is linked to various skin and hair disorders, indicating a need for cosmetics with natural adsorbents to reduce pollutant effects, achieving 30-55% removal efficiency.
6 citations
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August 2025 in “Frontiers in Bioengineering and Biotechnology” This review discusses the evolution of platelet concentrates in regenerative medicine, highlighting a proposed function-driven classification that distinguishes three generations of PCs by biological activity rather than development order, with third-generation exosome-based therapies showing superior therapeutic efficacy over earlier formulations.
40 citations
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March 2022 in “Small” In an animal model, this study found that PEG hydrogels delivering M2 macrophage-derived exosomes effectively promoted M1 to M2 macrophage transition and enhanced wound healing.
5 citations
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November 2025 in “Biomolecules” This review examines the benefits of topical hyaluronic acid in cosmetic applications, noting its ability to penetrate the skin in low-molecular-weight forms and highlighting safety supported by clinical trials.
April 2024 in “Chemical engineering journal” In this study, a novel injectable hydrogel with antibacterial and hemostatic properties showed promise in promoting the healing of MRSA-infected skin wounds.
32 citations
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June 2024 in “Pharmaceutics” This review explores the use of topical and transdermal delivery for drugs and cosmetics, highlighting the benefits of avoiding side effects and rapid metabolism, with a focus on nanoparticulate formulations and techniques for studying skin penetration.
3 citations
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February 2024 in “International journal of molecular sciences” This review highlights the potential of valorizing citrus by-products, particularly hesperidin from orange peels, as sustainable ingredients in skincare for antiaging, pigmentation, wound healing, and UV damage protection, emphasizing hesperidin's role in a circular economy approach.
2 citations
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July 2024 in “Materials Today Communications” In this study, an injectable alginate hydrogel with Fibronectin3 was developed, demonstrating high biocompatibility and ability to enhance wound healing in mice, suggesting promise for clinical application in treating irregular wounds.
January 2026 in “Research” This review discusses advanced biomedical technologies, such as nanotechnology and stem cell-based approaches, for treating androgenetic alopecia, detailing their benefits, current applications, and challenges, without reporting new experimental results.
1 citations
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December 2022 in “Middle East Journal of Science” This review covers hair dye formulations, their mechanisms, and potential applications, but reports no new findings; the authors highlight the process of oxidative dyeing and repairing damaged hair.
22 citations
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October 2019 in “International Journal of Nanomedicine” This study suggests that the hydrogel nanoparticle formulation of hair growth-promoting compounds may enhance hair follicle penetration and induce hair growth in tested models, demonstrating its potential as a hair growth treatment.
18 citations
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January 2016 in “Elsevier eBooks” This chapter reviews nanotechnology in cosmetics, detailing various formulations, performance assessment methods, and evolving regulations, while discussing safety, stability, and effectiveness concerns; it reports no new experimental results.
83 citations
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June 2020 in “Materials & Design” In this study, ACF sponges with 10% fucoidan significantly promoted wound healing and hair follicle regeneration in rats, showing improved hemostatic and antibacterial performance compared to other formulations.
5 citations
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August 2025 in “Drug Delivery and Translational Research” This review discusses lipid-polymer hybrid nanoparticles for dermatological applications, outlining their structural and formulation advancements, but reports no new clinical results and calls for further research on their therapeutic potential.
January 2026 in “Regenerative Biomaterials” This study highlights that hydrogel formulations unexpectedly prolonged healing in trials, pointing to a need for design based on detailed pathophysiological insights rather than empirical methods, and suggests technologies like AI materials optimization and 3D bioprinting to aid their clinical use for cancer survivors.
8 citations
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January 2025 in “Gels” This study developed cilostazol-loaded formulations for nose-to-brain delivery, finding that these formulations improved cilostazol's bioavailability by enhancing solubility, absorption, and permeability, achieving nearly 100% drug release in vitro within 2 hours.
169 citations
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October 2020 in “Pharmaceutics” This review discusses recent advancements in formulating electrospun nanofibers as wound dressings, emphasizing their advantages in incorporating bioagents for improved healing, but reports no new clinical results.
45 citations
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March 2020 in “International Journal of Nanomedicine” This study found that nanoemulsion-based formulations, such as nanoemulgel and NFs, might serve as promising topical delivery systems for treating inflammatory diseases, potentially offering an alternative to traditional nonsteroidal anti-inflammatory drugs, which are associated with adverse effects.
30 citations
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March 2016 in “European Journal of Pharmaceutical Sciences” This study found that using drug microplates in transdermal finasteride films enhances aqueous solubility and skin permeation compared to films with pure finasteride.
11 citations
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June 2025 in “Polymers” This review reports on recent surfactant-based niosome formulations, including those with polysaccharides, for versatile drug delivery applications such as ocular, oral, and transdermal settings, while discussing their limitations and potential prospects.
5 citations
,
February 2022 in “Acta Biomaterialia” This review highlights the potential of nanotechnology-based formulations in hair care and treatment, emphasizing how these innovative materials can enhance the stability, efficacy, and safety of active compounds while addressing the limitations of conventional formulations.
1 citations
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January 2024 in “Fibrosis” This review examines advancements in hydrogel formulations aimed at preventing dermal fibrosis and promoting scarless wound healing, highlighting their role in regulating myofibroblast differentiation and controlling the wound microenvironment.
47 citations
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January 2017 in “RSC Advances” Keratin peptides can change hair shape gently without harsh chemicals.
19 citations
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January 2023 in “ACS Omega” This study developed sodium alginate and epigallocatechin gallate cryogels cross-linked with ferric ions, showing that they have strong antibacterial properties and rapid hemostatic abilities, making them promising candidates for wound dressing applications.