May 2026 in “Commagene Journal of Biology” This review found that anti-aging peptides show promise in cosmeceuticals due to their targeted actions to rejuvenate skin, but challenges like peptide stability, penetration, and limited clinical data limit their current effectiveness.
January 2026 in “The Eurasian Journal of Life Sciences” This review discusses recent advances in the development of electrospun pectin nanofibers for biomedical applications, highlighting strategies to improve their mechanical properties and biological functions and addressing challenges like material variability and regulatory issues.
January 2026 in “RSC Advances” The hydrogel helps heal wounds without scars by releasing two drugs gradually.
In this study, a pH-responsive microneedle patch was developed, showing potential in rat models for treating spinal cord injuries by reducing inflammation, promoting nerve regeneration, and supporting neurogenesis, which contributed to improved motor and neurological recovery.
202 citations
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June 2005 in “Aaps Pharmscitech” This review discusses the potential of lecithin organogels for improving topical drug delivery and presents no new experimental results; the authors highlight their stability and low skin irritancy as advantages.
41 citations
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September 2017 in “Advanced Healthcare Materials” This study found that the DexIEME hydrogel promotes complete skin regeneration and scar attenuation in murine and porcine models, suggesting potential for treating deep dermal injuries.
21 citations
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April 2012 in “European Journal of Pharmaceutics and Biopharmaceutics” This study suggests that gel containing OSF3 loaded in niosomes offers high transfollicular penetration for topical anti-androgenic alopecia treatment with minimal systemic effect.
20 citations
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March 2023 in “Drug Delivery and Translational Research” This study found that a lacticin 3147 solid lipid nanoparticle gel demonstrated potent and sustained antimicrobial activity against S. aureus, including MRSA, in ex vivo S. aureus-infected pig skin.
10 citations
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June 2018 in “Aaps Pharmscitech” The flutamide-loaded hydrogel is a promising, skin-friendly treatment for acne and hair loss, potentially requiring less frequent application.
3 citations
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March 2023 in “National Journal of Health Sciences” This article reviews the potential of platelet-rich plasma therapy in managing diabetic foot ulcers but reports no new clinical findings, highlighting the need for further controlled trials to evaluate its effectiveness.
1 citations
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December 2023 in “Annals of Phytomedicine An International Journal” In this review, the researchers discuss how nanoemulgel overcomes the limitations of lipophilic phytomolecules by improving their bioavailability, penetration, and therapeutic efficacy, making it a promising nanocarrier for the treatment of various health conditions.
April 2026 in “BMC Biotechnology” This study found that curcumin spanlastics demonstrated greater antimicrobial, antioxidant, and anticancer activities in the MCF-7 breast cancer cell line compared to curcumin alone or curcumin nanocrystals, also affecting several cancer-related protein markers and showing enhanced solubility and activity.
January 2011 in “Side effects of drugs annual” Tretinoin gel is safe for sun exposure, but tacalcitol doesn't significantly improve non-segmental vitiligo.
21 citations
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January 2018 in “PLoS Genetics” This study found that certain keratin gene mutations associated with pachyonychia congenita are linked to altered enamel structure and increased risk of dental caries.
8 citations
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April 2019 in “ACS Biomaterials Science & Engineering” This study found that a new SIS-PEG sponge promoted rapid skin defect healing in mice and showed potential for reconstructing reconstituted skin with regenerated hair.
7 citations
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November 2022 in “Communications biology” This study found that injecting keratin into the skin of mice promoted hair growth, potentially through keratin's interaction with hair-forming cells and changes in the microenvironment.
7 citations
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February 2018 in “InTech eBooks” This article reviews how biomaterials and stem cells could advance regenerative medicine but does not report new results, emphasizing the potential of combining novel biomaterials with stem cells for effective therapies.
2 citations
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August 2016 in “Química Nova” This study concluded that chitosan nanoparticles loaded with minoxidil effectively target hair follicles and reduce dermal exposure compared to iontophoresis, despite similar drug delivery potential to the follicles.
January 2022 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” This article presents an overview of uncombable hair syndrome, emphasizing its clinical and molecular characteristics and noting systemic manifestations such as neuropsychiatric, ophthalmic, and cardiopulmonary issues.
January 2016 in “Springer eBooks” New materials and methods could improve skin healing and reduce scarring.
158 citations
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August 2011 in “Reviews in endocrine and metabolic disorders” This review examines the functions of vitamin D and its receptor in skin and explores how these are regulated, reporting no new clinical results.
117 citations
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November 2006 in “Experimental Dermatology” This review explores the biology of wool follicles and suggests their potential use as research models in modern biology, but it reports no new findings.
45 citations
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March 2020 in “ACS Applied Materials & Interfaces” In this study, researchers created a novel fibrous membrane inspired by ancient Chinese medicine that effectively promotes hair follicle regeneration and wound healing in deep burn injuries by releasing quercetin, copper, and silicon ions.
October 2023 in “Animal production science” This study investigated how vitamin A deficiency, certain diseases, and pregnancy affect cattle coat hair structure, finding notable keratin fibril interference under vitamin A deficiency and structural modifications in chronic renal failure, while pregnant cows exhibited superior hair tensile strength compared to non-pregnant ones.
June 2023 in “Historical records of Australian science/Historical Records of Australian Science” This biographical abstract highlights George Rogers' pioneering contributions to the understanding of keratin molecular structure and keratinisation biochemistry, including the application of electron microscopy to hair ultrastructure and the discovery of enzymes and gene transcription processes relevant to keratin proteins.
January 2018 in “Stem cell biology and regenerative medicine” This review discusses the interplay between signaling/transcription factor-mediated and epigenetic mechanisms in skin development and regeneration, highlighting the need for further exploration of epigenome reorganization in these processes.
2 citations
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December 2022 in “Journal of toxicologic pathology” This review outlines the histological structures of the skin, highlighting species and regional differences in dermal absorption and obstacles encountered in toxicological assessments due to epidermal thickness variability, contact dermatitis reactions, and stem cell vulnerabilities.
61 citations
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January 2018 in “Cosmetics” This review highlights the potential of coffee silverskin's bioactive compounds in combating skin aging and related conditions, suggesting it as a promising natural ingredient for cosmetics due to its antioxidant, anti-inflammatory, and anti-aging properties.
January 2026 in “PubMed Central” This article reviews self-assembled nanoparticles, highlighting their promising role in drug delivery systems but noting the need for further research on stability and large-scale industrial application; it reports no new clinical findings.
15 citations
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August 2020 in “Analytical chemistry” This study observed that lipids in human hair accumulate in specific areas and do not significantly impact water permeability, highlighting the utility of AFMIR for studying complex biomaterials.