June 2024 in “Skin Appendage Disorders” In this study, injections of PRP and MZT products significantly improved hair thickness, density, and count in AGA patients over six months, with variability observed in the extent of improvement between different formulations.
March 2024 in “Stem cell research & therapy” This study found that conditioned medium from human dental pulp stem cells (particularly under hypoxic conditions) improved keratinocyte survival and hair regrowth in a chemotherapy-induced alopecia mouse model and did not promote tumor growth, suggesting potential for safe therapeutic use.
November 2023 in “Stem cells and cloning” This study reported that adipocyte-derived mesenchymal stem cells-conditioned media significantly improved hair density, thickness, and follicular hair units in telogen effluvium patients, with positive outcomes in 70%-92% of cases, regardless of age.
August 2023 in “Stem Cell Research & Therapy” In this study on male androgenetic alopecia, the researchers reported significant increases in hair count, density, and thickness with minimal side effects over 6 weeks using adipose-derived stem cell conditioned media and minoxidil, but found no significant differences between concentrated and non-concentrated treatments.
May 2023 in “Clinical, Cosmetic and Investigational Dermatology” In this study, human dermal fibroblast-conditioned medium was found to contain numerous proteins involved in wound repair and hair regeneration, with identified proteins forming interaction networks linked to key signaling pathways like epidermal growth factor receptor and transforming growth factor-β.
April 2018 in “The Journal of Urology” This study found that phosphodiesterase inhibitors may suppress the proliferation of benign prostatic hyperplasia epithelial cells by modulating CCL5 levels in low androgen conditions.
January 2018 in “프로그램북(구 초록집)” This study found that applying adipocyte-derived stem cell conditioned media increased hair count significantly in androgenic alopecia patients compared to saline, suggesting it as a potential treatment, with no adverse effects reported.
In this study, subcutaneous injection of mesenchymal stem cell-conditioned medium promoted regeneration of mice skin aged by D-galactose, improving skin thickness, vascularization, and collagen density.
This study found that topical mesenchymal stem cell conditioned medium improved skin structure by increasing collagen fiber density, hair follicles, and blood vessel number in a mouse model of skin aging.
October 2012 in “Institutional Repositories DataBase (IRDB)” The researchers reported that treatment with adipose-derived stem cell conditioned medium significantly increased hair count in the study participants, suggesting it is an effective therapy for hair regeneration.
January 2011 in “Medical Journal of National Defending Forces in Northwest China” This study found that hypodermic injections of human dermal papilla cells conditioned medium led to hair regrowth in women with androgenetic alopecia, with an effective rate of 83.33%.
80 citations
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March 2008 in “Contact Dermatitis” This study found that scalp sensitivity frequently occurs in the French population and is associated with various symptoms and triggers, differing from facial skin sensitivity.
18 citations
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November 2013 in “Molecules and Cells” This study found that a novel 3D in vitro culture condition improved stemness markers and proliferation potential in human dermal stem/progenitor cells compared to traditional 2D methods.
12 citations
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January 2013 in “Indian Journal of Dermatology” This case report on a 13-year-old boy with monilethrix observed slight improvement after a two-month trial of oral N-acetyl cysteine, but overall hair density did not improve further.
6 citations
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January 2005 in “Han-guk hyeonmigyeong hakoeji/Applied microscopy” This study found that the 16th-century mummified hair from a female mummy in Paju was remarkably well-preserved, with the hair's ultrastructural features maintained likely due to a calcium-rich surface coat.
1 citations
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August 2023 in “Clinical, Cosmetic and Investigational Dermatology” In this study, researchers observed that a hidden scalp condition could contribute to acne keloidalis nuchae and potentially other primary cicatricial alopecias, impacting their diagnosis and treatment.
1 citations
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January 2004 in “Cosmetics and toiletries” Polyquaternium-64 helps damaged hair look healthy again.
January 2025 in “Open Veterinary Journal” This case report described an 8-year-old Chihuahua with significant hair loss, where supplementation with horse placenta extract, taurine, and vitamin B complex led to marked hair regrowth and maintained coverage during a 76-week follow-up period, suggesting a potential non-invasive treatment option for alopecia in dogs.
January 2021 in “Annals of Chinese medicine” This article compares Chinese medicine theories with male androgenetic alopecia progression and reports no new clinical results, noting an overlap in MAA pathogenesis with some COVID-19 conditions and proposing acupuncture points for treatment.
This study found that genetic ablation of Tslp in an AEC mutant mouse model reduced skin inflammation and improved survival, suggesting potential therapeutic benefits for AEC syndrome patients.
January 2012 in “Modern Plastic Surgery” This review discusses Toe Tourniquet Syndrome, a frequently misdiagnosed condition that can lead to necrosis if untreated, and calls for increased clinician awareness, but reports no new clinical findings.
October 2010 in “Reproductive Biomedicine Online” This study reported that MALDI-TOF Mass Spectrometry profiling demonstrated nearly 100% sensitivity and specificity in detecting adenomyosis and leiomyoma, revealing potential peptide markers for these conditions.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated the effectiveness of three formulated hair conditioners—Herbal, Synthetic, and Ayurvedic—using organoleptic and physicochemical tests like pH, Dirt Dispersion, and Stability, with the main aim to develop a product that meets user compliance and desired hair care effects.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this research, the authors developed and tested three types of hair conditioners—Herbal, Synthetic, and Ayurvedic—by analyzing their organoleptic properties and physicochemical parameters to assess their effects on hair manageability and appearance.
April 2024 in “International Journal of Science and Research Archive” This study focused on developing an effective herbal hair conditioner using ingredients like Custard Apple, Aloe Vera, and Hibiscus Flower, and evaluated its properties such as pH, stability, and moisturizing efficacy.
January 2011 in “Web journal anti-aging medicine/Anti-aging medicine” In this study, kamishoyosangoshimotsuto extract improved skin moisture, texture, and brightness, as well as hair thickness and strength in women with skin and scalp hair problems over 24 weeks.
23 citations
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June 2015 in “Oncology Letters” This study reported that adipose-derived stem cell-conditioned medium demonstrated anti-tumorigenic effects on B16 melanoma cells both in vitro and in vivo, indicating potential for future melanoma treatment.
3 citations
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September 2024 in “Brain and Behavior” This study found that combining ASA with conditioned medium from adipose tissue-derived MSCs may offer a promising approach for protecting against hippocampal injuries, suggesting potential synergistic therapeutic benefits that merit further investigation.
1 citations
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October 2023 in “Journal of Mind and Medical Sciences” This review discusses Barrett's esophagus, its risk factors, diagnostic methods, and treatment options, emphasizing its potential for malignant degeneration and the importance of personalized treatment based on patient factors.
February 2009 in “Journal of The American Academy of Dermatology” This study found that fractional infrared technology may improve skin laxity and thickness in the cervical area without side effects in a small group of patients.