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570-600 / 850 resultsresearch Micro-RNA-31 Controls Hair Cycle-Associated Changes in Gene Expression Programs of the Skin and Hair Follicle
miR-31 regulates hair growth by controlling gene expression in hair follicles.
research Voltammetric Sensing of Minoxidil Using a Molecularly Imprinted Polymer (MIP)-Modified Carbon Paste Electrode
A new sensor can detect minoxidil accurately and effectively.
research CUBIC Protocol Visualizes Protein Expression at Single Cell Resolution in Whole Mount Skin Preparations
The CUBIC protocol allows detailed 3D visualization of proteins in mouse skin biopsies.
research Mathematical Model for Alopecia Areata
The model showed that immune system guardians and the cytokine interferon-γ are key in alopecia areata progression.
research Proteomics Analysis of the Secondary Hair Follicle Cycle in Liaoning Cashmere Goat
The study found specific proteins that could mark different growth stages of cashmere goat hair and may help improve cashmere production.
research Targeting the Undifferentiated State of Cancer
Less differentiated melanoma cells are more vulnerable to a type of cell death, which could improve cancer treatments.
research Ficus Benghalensis as Potential Inhibitor of 5α-Reductase for Hair Growth Promotion: In Vitro, In Silico, and In Vivo Evaluation
Ficus benghalensis leaf extracts can effectively promote hair growth and inhibit hair loss.
research Automating Hair Loss Labels for Universally Scoring Alopecia from Images
The AI system HairComb accurately scores hair loss severity, matching dermatologist assessments.
research Is Dutasteride a Therapeutic Alternative for Amyotrophic Lateral Sclerosis?
Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.
research Body Site Heterogeneity and Microbial Diversity Is Lost in Individuals with Hidradenitis Suppurativa
People with Hidradenitis Suppurativa have less diverse skin bacteria and different bacterial metabolism than healthy individuals.
research Exploring Diachronic Changes of Biomedical Knowledge Using Distributed Concept Representations
The document concluded that biomedical knowledge changes over time and the study evaluated a new method to track these changes.
research Molecular Docking Study of Phytochemical Compounds from Kushtakudori Ennai as a Potential Anti-Alopecia Treatment
Certain compounds from Kushtakudori ennai may help treat hair loss.
research A Machine Learning-Based Scalp Hair Inspection and Diagnosis System for Scalp Health
The system can automatically identify different hair and scalp conditions using machine learning.
research Logic-Based Modeling and Drug Repurposing for the Prediction of Novel Therapeutic Targets and Combination Regimens Against E2F1-Driven Melanoma Progression
Cialis and Finasteride could be repurposed to treat aggressive melanoma.
research A Multi-Scale Spatial Atlas of Human Skin Links Cancer Cell States to Site of Origin
The research shows that skin cancer likely originates from hair follicles and that certain cell populations expand to promote skin cancer growth.
research Structural Basis for the Catalysis and Inhibition of Human Steroid 5α-Reductase 2
The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.
research Reliability of the Estimation of the Take of Split Thickness Graft by the Observation Method
The traditional method of estimating skin graft success by looking is generally reliable but less so for inexperienced observers and in certain wound conditions.
research Molecular Phenotyping of Lichen Planopilaris Revealed Dysregulation of Cholesterol/Fatty Acid Metabolism, Fibrosis, and Mast Cell Pathways
Lichen planopilaris involves disrupted fat metabolism, increased scarring, and mast cell activity.
research Repurposing of Drugs as Novel Influenza Inhibitors from Clinical Gene Expression Infection Signatures
Existing drugs, including a blood pressure medication, show promise as new treatments for influenza.
research Faculty Opinions Recommendation of Investigation of Four Novel Male Androgenetic Alopecia Susceptibility Loci: No Association with Female Pattern Hair Loss
The research found that certain genes are linked to male pattern baldness, but these same genes do not affect female pattern hair loss.
research Faculty Opinions Recommendation of Six Novel Susceptibility Loci for Early-Onset Androgenetic Alopecia and Their Unexpected Association with Common Diseases
Six new genes linked to early hair loss were found, which also surprisingly connect to Parkinson's disease and lower fertility.
research Faculty Opinions Recommendation of Six Novel Susceptibility Loci for Early-Onset Androgenetic Alopecia and Their Unexpected Association with Common Diseases
Six new genes linked to early hair loss were found, which also surprisingly connect to Parkinson's disease and lower fertility.
research Faculty Opinions Recommendation of Six Novel Susceptibility Loci for Early-Onset Androgenetic Alopecia and Their Unexpected Association with Common Diseases
Six new risk spots for early hair loss were found, which also link to Parkinson's disease and lower fertility. Two genes, FOXA2 and HDAC4, could be new treatment targets. Hair loss might also be connected to heart disease, metabolic syndrome, and prostate cancer.
research The JAK/STAT Signaling Pathway: From Bench to Clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research Epithelial-Mesenchymal Micro-Niches Govern Stem Cell Lineage Choices
Different small areas within hair follicles send specific signals that control what type of cells stem cells become.
research FGF5 Is a Crucial Regulator of Hair Length in Humans
FGF5 gene mutations cause unusually long eyelashes by affecting hair growth regulation.
research Identification of Dkk4 as a Target of Eda-A1/Edar Pathway Reveals an Unexpected Role of Ectodysplasin as Inhibitor of Wnt Signaling in Ectodermal Placodes
Ectodysplasin inhibits Wnt signaling to help form hair follicles.
research Chemical Screening for Hair Cell Loss and Protection in the Zebrafish Lateral Line
PROTO1 and PROTO2 protect against hearing damage.
research In Vitro Assembly and Structure of Trichocyte Keratin Intermediate Filaments
Scientists successfully created mouse hair proteins in the lab, which are stable and similar to natural hair.