2 citations
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March 2023 in “3C Empresa Investigación y pensamiento crítico” In this study, patients with alopecia areata showed significantly elevated serum levels of IFN-γ and severely deficient vitamin D3 levels compared to healthy controls.
64 citations
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May 2000 in “International Journal of Dermatology” This study found that thalidomide increased peripheral lymphocyte counts and reduced inflammation in lupus erythematosus patients, but was associated with polyneuropathy, suggesting careful use in refractory cases.
16 citations
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May 1998 in “International Journal of Dermatology” This study found that elevated serum cortisol levels and other immunological changes are significantly involved in the active phases of psoriasis eruptions.
May 2024 in “International journal of medicine and psychology.” This study found that in laboratory rats, toxic concentrations of hydrogen sulfide affected the immune system differently depending on age and immune suppression status, with notable changes in immune cell levels and phagocytosis, suggesting significant roles in age-associated pathologies.
June 2024 in “Research Square (Research Square)” This study found that among patients with systemic lupus erythematosus, the absence of skin rash and low levels of complement C3 were significant risk factors for developing lupus nephritis, with their combination demonstrating good predictive diagnostic value.
39 citations
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September 2017 in “The Open Rheumatology Journal” This review discusses the role of complement activation in SLE and suggests that while monitoring C3 and C4 remains important, increased levels of cell-bound complement activation products may better indicate disease activity.
5 citations
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February 1977 in “Archives of Dermatology” This study reports that 14 of 19 patients with erythema nodosum leprosum had C3 deposits in vessel walls when examined using direct immunofluorescence.
May 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reported that specific inhibition of the classical complement pathway with BIVV009 prevented C3 deposition along the dermal-epidermal junction in bullous pemphigoid, reflecting its potential efficacy.
71 citations
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May 2019 in “Rheumatology” This study observed that PD-1+CXCR5-CD4+T peripheral helper cells are significantly elevated in patients with systemic lupus erythematosus and are correlated with disease activity indicators, suggesting their potential role in lupus pathogenesis.
May 2025 in “The Journal of Rheumatology” This case report describes a patient with systemic lupus erythematosus whose unusual nephrological presentation led to a diagnosis of C3 glomerulopathy, highlighting the importance of considering atypical findings to broaden diagnostic approaches.
1 citations
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April 2025 in “Tropical Journal of Natural Product Research” In this study, researchers using network pharmacology and molecular docking methods found that compounds from Avicennia Marina could inhibit hepatitis C virus infection by targeting key proteins such as AKT1 and TNF-α, showing potential for anti-HCV treatments.
August 2025 in “Scientific Reports” This study found that the protein C4BPA may link insulin resistance and acne vulgaris by influencing lipid metabolism and inflammatory pathways, suggesting it as a potential mediator in the pathogenesis of both conditions.
41 citations
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August 1988 in “Journal of The American Academy of Dermatology” In this case report, a patient with subacute cutaneous lupus erythematosus and exfoliative erythroderma achieved complete remission with systemic corticosteroids and long-term hydroxychloroquine.
17 citations
,
March 2020 in “Frontiers in Chemistry” This study isolated new geranylated coumarins from Mammea siamensis flowers and found that several of these compounds inhibit testosterone 5α-reductase.
1 citations
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January 2018 in “Skin appendage disorders” This review discusses the role of the complement pathway in alopecia areata and reports no new clinical results; the authors suggest that targeting this pathway could offer treatment options.
March 2023 in “Journal of pharmacognosy and phytochemistry” This study identified numerous nutraceutical components in unripe fruits of three Musa species, potentially valuable for developing pharmaceuticals that promote human health.
This monograph reviews the historical and contemporary use of pomegranate in medicine, detailing its chemical components and applications across various medical fields including oncology, dentistry, and urology.
1 citations
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January 2019 in “Open Journal of Internal Medicine” This case report describes a 19-year-old patient with systemic lupus and a composite heterozygosis SC with thalassemic component, highlighting the diagnostic challenge when symptoms of both conditions occur simultaneously.
May 2024 in “Molecules/Molecules online/Molecules annual” This narrative review reports that well-selected plant extracts and their active compounds may improve hair health by promoting hair growth and preventing hair loss, potentially aiding in developing targeted therapies for alopecia.
This review highlights the potential of plant-derived natural compounds as biocompatible and biodegradable materials in dermal and transdermal delivery systems, emphasizing their unexplored benefits and detailing recent advances in isolation techniques and drug delivery technologies.
14 citations
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April 2021 in “Biology” This study found that ethanol extract of Tubtim Chumphae rice bran downregulates SRD5A gene expression, similarly to finasteride, suggesting potential use as an anti-hair loss product.
5 citations
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May 2025 in “Scientific Reports” This study found that extracts from Indian gooseberry leaves showed strong antimalarial activity against Plasmodium falciparum, with low cytotoxicity, suggesting potential for developing new antimalarial drugs.
May 1991 in “Current problems in dermatology” This article reviews the relationship between the skin and the immune system and discusses how skin manifestations can indicate immunodeficiencies but reports no new research findings.
30 citations
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March 2019 in “Archives animal breeding/Archiv für Tierzucht” In this study, variation in the KRTAP15-1 gene in goats was linked to changes in cashmere fibre diameter, with specific variants showing dominant or recessive effects.
27 citations
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November 2021 in “Scientific Reports” This study used bioinformatics to explore molecular differences in testicular and ovarian responses to SARS-CoV-2, identifying genes that could be associated with sex differences in infection outcomes.
169 citations
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June 2010 in “Molecular & cellular proteomics” This study suggests that ethylene and lignoceric acid (C24:0) may promote cotton fiber and Arabidopsis root hair growth by activating the pectin biosynthesis network.
This study found that γδ T cells play a role in regulating stromal behavior, influencing the composition and vascularity of fibrotic tissues during the foreign body response.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study constructed a comprehensive atlas of prenatal human skin, revealing that innate immune cells, such as macrophages, play a crucial role in skin morphogenesis by interacting with non-immune cells, influencing hair follicle formation and angiogenesis beyond their traditional immune functions.
1 citations
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January 2025 in “Frontiers in Oncology” This review highlights REV7's crucial roles in maintaining genome stability, its implication in several cancers, and its association with poor prognoses and treatment resistance, while also noting that REV7 suppression may improve chemotherapy sensitivity.
3 citations
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August 2023 in “Molecules” This study found that components derived from Sansevieria trifasciata demonstrated notable antibacterial activity against Escherichia coli and Streptococcus aureus, highlighting potential for developing new antibacterial agents.