Hemoglobinopathy and Systemic Lupus: A Rare Association

    January 2019 in “ Open Journal of Internal Medicine ”
    Assétou Kaya Soukho, Ibrahima Amadou Dembélé, Aldiouma Guindo, D Traoré, Nounga Romuald Nyanke, Djibril Sy, Abasse Sanogo, Mamadou Cissoko, Barry Boubacar Sangaré, Mamadou Malle, Samba Cisse, Abdramane Traoré, Mahamadou Saliou, Nanko Doumbia, Bréhima Boly Berthé, Keïta Kaly, Boubacar Zoumana Cisse, Drissa Sangaré, Youssouf Fofana, Kokou Tbah Tighankpa, Adramé Keita, Mamadou Almamy Keita, Mamadou Dembélé, Abdel Kader Traoré, Hamar Alassane Traoré
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    TLDR Diagnosing both systemic lupus and hemoglobinopathy is challenging due to overlapping symptoms.
    The document reported a case of a 19-year-old patient with systemic lupus and a composite heterozygosis SC with a thalassemic component. The patient exhibited symptoms including anemia, polyarthralgia, macular erythematous lesions, photosensitivity, alopecia, pubic and axillary hair loss, and painful joint swelling. Hemoglobin electrophoresis revealed a compound heterozygote SC with β thalassemia, and antinuclear antibodies were positive with an anti-Sm positive antibody. The authors concluded that diagnosing both conditions can be challenging when symptoms overlap.
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