February 2026 in “Journal of Aesthetic Medicine” This narrative review concluded that facial aging involves complex anatomical changes that require multimodal rejuvenation approaches, integrating fillers, collagen stimulators, botulinum toxin, and energy-based devices for effective results, while emphasizing the need for scientific evidence and patient safety in aesthetic treatments.
3 citations
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June 2017 in “Aesthetic plastic surgery” This study reported that novel adipose slurry injections improved rhytides and dermis density in patients receiving facial wrinkle treatments based on evaluations at multiple follow-up intervals.
18 citations
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February 2023 in “Plants” This study found that PES1CMU-defatted rice bran (DFRB) showed effective skin whitening and anti-aging properties comparable to standard treatments in cell models, suggesting its potential use in dermatocosmetics.
1 citations
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November 2022 in “Experimental cell research” This study found that a PGE2 matrix, when injected subcutaneously, increased the proportion of developing hair follicles and improved hair follicle stem cell markers in a mouse model of hair loss.
12 citations
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November 2015 in “Journal of Investigative Dermatology Symposium Proceedings” PTH-CBD helps reduce hair loss in mice by stimulating hair growth directly.
January 2015 in “Journal of clinical & experimental dermatology research” This study found that treatment with PTH-CBD stimulated hair growth in mice with alopecia areata, with increased levels of beta catenin indicating activation of the Wnt pathway.
59 citations
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September 2011 in “Lasers in Medical Science” This study concluded that the 800-nm diode laser is effective in enhancing skin structure and collagen expression via the TGF-β/Smad pathway, suggesting potential for non-ablative rejuvenation.
2 citations
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March 2005 in “Journal of the American Academy of Dermatology” Equol may help with antiaging and skin health by boosting collagen and blocking certain hormones.
August 2026 in “Pharmacological Research - Modern Chinese Medicine” In this study, topical applications of Agrimonia pilosa extract and agrimonolide demonstrated notable anti-inflammatory and wound healing benefits in animal models, significantly reducing inflammation and enhancing wound closure compared to controls. However, further research in humans is needed to confirm these preclinical findings.
August 1993 in “Journal of Dermatological Science” 8 citations
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March 2013 in “Cell Transplantation” In this study, intradermal injection of GCSF-mobilized peripheral blood stem cells from young pigs rejuvenated skin in aged pigs by increasing collagen, elastin, and cell renewal rates.
29 citations
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November 2014 in “Experimental Dermatology” This study found that α-MSH administration before skin wounding in adult mice reduced inflammation and scar area, suggesting a potential pathway to more regenerative healing.
16 citations
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May 2006 in “PubMed” This article reviews the diverse regulatory roles of alpha-melanocyte-stimulating hormone in skin biology, highlighting its potential involvement in maintaining tissue homeostasis and protecting against inflammation-induced DNA damage but reports no new clinical findings.
3 citations
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November 2022 in “International journal of molecular sciences” This study reported that bio-pulsed avian-derived mesenchymal stem cell extracellular vesicles significantly improved cell proliferation, wound healing, and gene expression in human skin fibroblasts and hair follicle cells.
1 citations
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January 2005 in “Experimental Dermatology” This study found that α-MSH may suppress IFN-γ-driven upregulation of ICAM-1 in human dermal fibroblasts, suggesting potential roles for melanocortins in inflammatory skin disorders beyond collagen synthesis effects.
July 2026 in “International Journal of Pharmaceutics X” In this study, researchers developed a biopolymer-based dual-layer wound dressing that significantly improved healing outcomes in a 14-day rat model, reporting 94% wound closure by day 15 and enhanced tissue regeneration, swelling properties, and cell viability.
September 2025 in “Cell Reports” This study found that a single instance of acute skin stretching can enhance immune surveillance and improve vaccine delivery by increasing skin permeability and promoting immune cell recruitment without causing tissue damage.
4 citations
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May 2019 in “Zeitschrift für Naturforschung C” This study found that Ishige sinicola extract stimulated osteoblast differentiation and bone formation in MC3T3-E1 cells, suggesting potential use for osteoporosis prevention and treatment.
July 2024 in “Journal of Investigative Dermatology” This study found that topically applied melatonin exerts significant anti-aging effects on human scalp skin ex vivo, including increased SIRT1 expression and reduced mTORC1 pathway activity.
23 citations
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October 2015 in “Plastic and reconstructive surgery/PSEF CD journals” This article reviews the author's experience and favored techniques for using Radiesse in cosmetic treatments but reports no new clinical trial results.
1 citations
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August 2024 in “Lasers in Surgery and Medicine” This study observed that calcium hydroxylapatite can be successfully incorporated and retained in the dermis for at least six weeks after fractional laser treatment, with new collagen forming around it.
September 2025 in “Editora Pasteur eBooks” This abstract discusses the broad scope of dermatology and aesthetic procedures, highlighting their significant multidisciplinary evolution within the health sciences, but it does not report specific study results.
December 2025 in “eScience” This study presents a new wireless bioelectronic system powered by ambient Wi-Fi signals that enhances wound healing by providing electrical stimulation and real-time monitoring, offering a promising solution for at-home treatment and regenerative therapy.
11 citations
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January 2013 in “Postępy Dermatologii i Alergologii” This review discusses various theories of skin aging and the importance of using professional and at-home skincare solutions, but offers no new empirical findings.
9 citations
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April 2019 in “Dermatologic Therapy” This study reviewed the effectiveness of long pulse 1,064-nm Nd:YAG laser treatments for leg veins, hair removal, and skin rejuvenation, highlighting its safety, particularly for darker skin types, due to reduced pigmentary side effect risks.
8 citations
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June 2022 in “International Journal of Molecular Sciences” This review discusses the potential of extracellular vesicles for facial aesthetic applications, including scar reduction and skin rejuvenation, but reports no new clinical results; further research into production and mechanisms is needed.
February 2026 in “Frontiers in Materials” In this study, researchers developed iron-curcumin-coordinated nanoparticles to enhance curcumin's bioavailability and therapeutic effects, finding that these nanoparticles accelerate wound healing in diabetic mice by reducing inflammation and oxidative stress more effectively than free curcumin.
25 citations
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August 1992 in “In vitro cellular & developmental biology” The new system can grow hair in the lab and test hair growth treatments.
32 citations
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October 2004 in “Experimental Dermatology” This study found that α-MSH acts as a modulator of inflammatory and fibrogenic responses in human fibroblastic skin cells, indicating potential therapeutic options for fibrotic skin disorders and inflammatory diseases of the hair follicle.
10 citations
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May 2016 in “bioRxiv (Cold Spring Harbor Laboratory)” This study observed that differences in the expression of genes related to lipid metabolism may play a major role in determining wool fiber diameter in sheep.