research Adult-Onset Porokeratotic Eccrine Ostial and Dermal Duct Nevus: Dermatoscopic Findings and Treatment with Tazarotene
An adult with a rare skin condition improved with tazarotene treatment.
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research Phenotypic Heterogeneity of Epidermolysis Bullosa Associated With the Recurrent Pathogenic Variant p.(Arg2000Trp) in Plectin
The specific skin disease variant p.(Arg2000Trp) in plectin can cause a wide range of symptoms, which should be considered when diagnosing patients.
research OsPHR2 Is Involved in Phosphate-Starvation Signaling and Excessive Phosphate Accumulation in Shoots of Plants
OsPHR2 gene causes excessive phosphate in rice shoots, affecting plant growth and root development.
research The Epidermis: Rising to the Surface
The document concludes that recent research has improved understanding of skin diseases and the balance between cell growth and differentiation in the epidermis.
research Epidermolysis Bullosa Simplex: A Paradigm for Disorders of Tissue Fragility
Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.
research Histochemical and Immunohistochemical Markers for Human Eccrine and Apocrine Sweat Glands: An Aid for Histopathologic Differentiation of Sweat Gland Tumors
Markers help differentiate between apocrine and eccrine sweat glands to identify sweat gland tumors.
research Bidirectional Binding Property of High Glycine–Tyrosine Keratin-Associated Protein Contributes to the Mechanical Strength and Shape of Hair
High glycine–tyrosine keratin-associated proteins help make hair strong and maintain its shape.
research Integrated miRNA-mRNA Analysis Reveals Regulatory Pathways Underlying the Curly Fleece Trait in Chinese Tan Sheep
Researchers found genes and microRNAs that control curly fleece in Chinese Tan sheep.
research Self-Consistent Field Theory for the Interactions Between Keratin Intermediate Filaments
Keratin filaments' elasticity is influenced by their terminal domains and surrounding medium.
research Biofabrication of Human Skin with Its Appendages
Current methods can't fully recreate skin and its features, and more research is needed for clinical use.
research The Expression of Equine Keratins K42 and K124 Is Restricted to the Hoof Epidermal Lamellae of Equus Caballus
K42 and K124 keratins are only found in horse hoof lamellae.
research Repetitive Transcranial Magnetic Stimulation for Treatment of Trichotillomania: Case Series
rTMS may help treat trichotillomania in some patients.
research New Insights Into Human Hair: SAXS, SEM, TEM, and EDX for Alopecia Areata Investigations
Alopecia Areata causes significant structural and compositional changes in hair.
research Acid Phosphatase Distribution in the Wool Follicle: Fate of Organelles in Keratinized Cells
Keratinized wool cells still have some organelles like lysosomes and mitochondria.
research Read-Through for Nonsense Mutations in Type XVII Collagen-Deficient Junctional Epidermolysis Bullosa
A new therapy for a skin blistering condition has not been developed yet.
research A General Mathematical Model for the In Vitro Assembly Dynamics of Intermediate Filament Proteins
The model shows that filament flexibility and amino acid differences affect how fast intermediate filament proteins assemble.
research Trichoscopy in Hair Disorders in Darker Skin: An Approach to Diagnosis
Trichoscopy is useful for diagnosing hair and scalp disorders in people with darker skin.
research The Swelling Behavior of Hair Studied Through the Structural Change of Keratin Protein During the Permanent Waving Treatment
Hair structure changes immediately during perm treatment, with initial damage partially restored later.
research Diagnosis and Differential Diagnosis of Tertiary Androgenetic Alopecia With Severe Alopecia Areata Based on High-Resolution MRI
High-resolution MRI can distinguish between tertiary androgenetic alopecia and severe alopecia areata by measuring scalp and tissue thickness and hair follicle depth.
research A Review of Keratin-Based Biomaterials for Biomedical Applications
Keratin from hair and wool is used in medical materials for healing and drug delivery.
research The JAK/STAT Signaling Pathway: From Bench to Clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research Spermidine/Spermine-N1-Acetyltransferase: A Key Metabolic Regulator
SSAT is a key enzyme affecting cell growth and metabolism, with potential but risky use in disease treatment.
research Genetically Altered Expression of Spermidine/Spermine N1-Acetyltransferase Affects Fat Metabolism in Mice via Acetyl-CoA
Altering SSAT affects fat metabolism and body fat in mice.
research Activated Polyamine Catabolism Depletes Acetyl-CoA Pools and Suppresses Prostate Tumor Growth in TRAMP Mice
Overexpressing SSAT enzyme reduces prostate tumor growth in mice.
research In Vitro Assembly and Structure of Trichocyte Keratin Intermediate Filaments
Scientists successfully created mouse hair proteins in the lab, which are stable and similar to natural hair.
research LGR5 Is a Marker of Poor Prognosis in Glioblastoma and Is Required for Survival of Brain Cancer Stem-Like Cells
High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.
research Scarless Wound Healing: Transitioning from Fetal Research to Regenerative Healing
Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.
research Alkylation of Human Hair Keratin for Tunable Hydrogel Erosion and Drug Delivery in Tissue Engineering Applications
Alkylation of human hair keratin allows for adjustable drug release rates in hydrogels for medical use.
research Defining the Cellular Environment in the Organ of Corti Following Extensive Hair Cell Loss: A Basis for Future Sensory Cell Replacement in the Cochlea
The conclusion is that genetic differences affect how the cochlea heals after hair cell loss, which may challenge the creation of hearing loss treatments.
research Keratins and Skin Disease: Genetic and Molecular Roles
Keratin mutations cause skin diseases and could lead to new treatments.