3 citations
,
July 2022 in “Brain and Behavior” This study observed that a CARASIL mouse model demonstrated abnormal behavior, vascular and cellular changes, and upregulation of the TGF-β/Smad signaling pathway, indicating its potential involvement in CARASIL pathogenesis.
20 citations
,
August 2015 in “Behaviour change” This study identified six belief themes that may contribute to hairpulling behavior in women with trichotillomania, suggesting an important role for cognitions in this disorder's phenomenology.
June 2025 in “British Journal of Dermatology” In this systematic review, the authors found that hair loss in women causes significant psychological distress, with supportive interventions like cognitive behavioral therapy and cosmetic solutions helping to reduce anxiety, improve coping, and enhance quality of life.
1 citations
,
March 2024 in “The Journal of Dermatology” In this study, a multidisciplinary psychodermatology service treating children and young people with compulsive hair pulling reported varied success, with 45.4% achieving complete resolution and 36.4% seeing substantial improvement, suggesting a hybrid care model may benefit patient engagement and therapy outcomes.
In this literature review, it was reported that mental health disorders may both contribute to and be exacerbated by various types of hair loss, and an interdisciplinary treatment model is recommended for effective diagnosis and patient care.
138 citations
,
March 2001 in “Clinics in Dermatology” This review discusses the relationship between perceived stress and hair loss or graying, exploring hair follicles as a model system but reports no new clinical results.
30 citations
,
January 1997 in “ILAR Journal” This review details the development and genetic background of senescence-accelerated mouse strains, provides a comprehensive examination of their phenotypes, and highlights their importance for aging research, but reports no new experimental results.
This study investigated the effects of ethanol leaf extracts from Ziziphus jujuba and Eclipta alba on cognitive impairments in diabetic rats, finding significant improvements in learning and memory with these treatments, along with decreased blood glucose levels over 21 days.
4 citations
,
January 2025 in “Translational Psychiatry” In this study, remote photobiomodulation therapy to the lungs improved behavioral and neurological outcomes in rats with repeated closed-head injuries, suggesting potential preventive benefits for brain health.
56 citations
,
July 2014 in “PLoS ONE” This study found that midazolam improved PTSD-associated behavioral deficits in rats through its action on the TSPO, CBR, and neurosteroidogenesis pathways.
28 citations
,
August 2009 in “Nursing for Women's Health” This review highlights that while healthcare providers are starting to diagnose polycystic ovary syndrome earlier in teens, the psychological and social needs often remain inadequately addressed.
3 citations
,
September 2022 in “Frontiers in psychiatry” This study found that stress and its related symptoms were highly prevalent among university students in Egypt during the third wave of the COVID-19 pandemic, with most reporting negative coping strategies.
1 citations
,
March 2016 in “Neurotoxicity Research” In this study, finasteride pretreatment led to EEG changes in rats that suggest a mild reduction in thioacetamide-induced hepatic encephalopathy.
63 citations
,
January 2010 in “Frontiers in Aging Neuroscience” This study found that 3alpha-diol, an androgen metabolite, improved cognitive and affective performance in aged male rats, suggesting its role in countering age-related decline in hippocampally-influenced behaviors.
237 citations
,
January 2010 in “The Journal of Sexual Medicine” The authors updated recommendations on diagnosing and treating women's sexual dysfunctions, emphasizing a comprehensive assessment approach, while noting the need for further multidisciplinary research.
21 citations
,
April 2015 in “Psychology Research and Behavior Management” This review evaluates various cognitive-behavioral interventions for trichotillomania but does not report new clinical findings, highlighting the need for further research on their efficacy.
9 citations
,
February 2016 in “Cambridge University Press eBooks” This chapter reviews the role of self in disorders related to the OCD spectrum, such as hoarding disorder, body dysmorphic disorder, and trichotillomania, and reports no new findings.
1 citations
,
May 2016 in “Current Opinion in Pediatrics” This review discusses diagnostic strategies for pediatric hair loss, emphasizing the importance of thorough examinations and dermoscopy for accurate diagnosis, and reports no new research findings.
December 2020 in “Current Sexual Health Reports” This review discusses the role of neurosteroids and androgens throughout different life stages, noting the potential disruptions caused by 5α-reductase inhibitors like finasteride, but no new clinical results are reported.
3 citations
,
December 2001 in “Irish Journal of Psychological Medicine” This review discusses trichotillomania, its diagnosis, prevalence, potential brain abnormalities, and current treatment options, and offers no new clinical findings.
2 citations
,
January 2023 in “Journal of Education, Health and Sport” In this study, researchers reviewed current treatments for trichotillomania and found that psychotherapy, particularly cognitive-behavioral therapy like habit reversal training, is most effective, with some medications helping to alleviate symptoms, though further study is needed on their use.
August 2025 in “MedScien” This study highlights factors contributing to increasing seborrheic alopecia among teenagers, including hormonal, lifestyle, and psychological influences, and suggests integrated treatment strategies including medication, lifestyle adjustments, and psychological interventions.
2 citations
,
July 2005 in “Baylor University Medical Center Proceedings” This case report diagnosed a 4-year-old girl with trichotillomania after observation of her twirling and pulling her hair at the affected site.
2 citations
,
July 2016 in “Pharmacopsychiatry” This case report describes a non-mosaic Turner-Syndrome individual with global cerebral atrophy, significant cognitive impairment, and severe treatment-resistant schizophrenia.
4 citations
,
June 2024 in “Journal of pharmacopuncture” This review compiles current experimental research on Alzheimer's and cognitive impairment models, highlighting the potential of *Polygonum multiflorum* for treating neurological disorders and suggesting a foundation for future clinical trials.
19 citations
,
March 2019 in “Behavioural Brain Research” This study found that repeated finasteride administration in male Wistar rats led to increased depression-like behavior, suggesting an animal model for investigating finasteride's neuropsychiatric effects is viable.
January 2026 in “Frontiers in Cellular Neuroscience” This study discusses the complex roles and effects of brain-synthesized sex neurosteroids, highlighting sex differences in their concentrations and their varied impacts on synaptic plasticity, cognitive behavior, and aging-related cognitive decline.
May 2026 in “AAPS PharmSciTech” This study found that PEGylated LUT-Aspasomes significantly improved neuroprotective effects in stressed rats, enhancing spatial memory, reducing depressive-like behavior, and preserving hippocampal architecture better than free luteolin. Additionally, it increased brain delivery and stability, suggesting potential for treating stress-related neurobehavioral disorders.
September 2025 in “Cosmoderma” This study highlights how the COVID-19 pandemic has exacerbated stress-related dermatological issues like acne and hair loss by affecting skin and hair cycles through stress hormones, emphasizing the need for comprehensive psychoneuroendocrine-informed approaches to diagnosis and treatment.
This case report chronicles a three-year journey of long COVID in a previously healthy 26-year-old, detailing treatment trials and near-total remission, but provides no new generalizable data.