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GlossaryPrefrontal Cortex

region of the brain responsible for decision-making and social behavior

The prefrontal cortex (PFC) is the front part of the brain's frontal lobes, located just behind the forehead. It is crucial for complex cognitive behaviors such as decision-making, problem-solving, and controlling social behavior. The PFC is also involved in personality expression and moderating social conduct, making it essential for planning and executing tasks.

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research Restricted effects of androgens on glucocorticoid signaling in the mouse prefrontal cortex and midbrain

3 citations , January 2024 in “Frontiers in Endocrinology”

research Pregnancy's Lasting Imprint: Late Pregnancy Allopregnanolone Alters Rat Fear Recall and Medial Prefrontal Cortex Activity

January 2026 in “Hormones and Behavior”

Pregnancy affects fear memory and brain activity in female rats.

research Detection of Circular RNA Expression and Related Quantitative Trait Loci in the Human Dorsolateral Prefrontal Cortex

48 citations , May 2019 in “Genome Biology”

Researchers found that certain RNA circles in the brain are linked to disease risk, but their exact role in disease is still unknown.

research Dietary Glucoraphanin Prevents the Onset of Psychosis in Adult Offspring After Maternal Immune Activation

36 citations , January 2018 in “Scientific reports”

Eating glucoraphanin can help prevent psychosis in offspring whose mothers had immune system activation.

research Hedonic Sensitivity to Natural Rewards Is Affected by Prenatal Stress in a Sex-Dependent Manner

28 citations , May 2015 in “Addiction Biology”

Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.

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