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    Glossary Prefrontal Cortex

    region of the brain responsible for decision-making and social behavior

    The prefrontal cortex (PFC) is the front part of the brain's frontal lobes, located just behind the forehead. It is crucial for complex cognitive behaviors such as decision-making, problem-solving, and controlling social behavior. The PFC is also involved in personality expression and moderating social conduct, making it essential for planning and executing tasks.

    Research 10 of 204

    1. Restricted effects of androgens on glucocorticoid signaling in the mouse prefrontal cortex and midbrain Frontiers in Endocrinology · 2024 · 3 citations
    2. Pregnancy's lasting imprint: Late pregnancy allopregnanolone alters rat fear recall and medial prefrontal cortex activity Hormones and Behavior · 2026
    3. Detection of circular RNA expression and related quantitative trait loci in the human dorsolateral prefrontal cortex Genome Biology · 2019 · 48 citations
    4. Prefrontal 5α-reductase 2 mediates male-specific acute stress response Science Advances · 2025 · 5 citations
    5. Dietary glucoraphanin prevents the onset of psychosis in the adult offspring after maternal immune activation Scientific reports · 2018 · 36 citations
    6. Hedonic sensitivity to natural rewards is affected by prenatal stress in a sex-dependent manner Addiction Biology · 2015 · 28 citations
    7. The Neurosteroidogenic Enzyme 5α-Reductase Mediates Psychotic-Like Complications of Sleep Deprivation Neuropsychopharmacology · 2017 · 27 citations
    8. Acetate meliorates depressive-like behaviour in a rat model of PCOS through suppression of HDAC2 expression and DNA methylation Research Square (Research Square) · 2022 · 1 citations
    9. Inhibition of 5α-reductase in the nucleus accumbens counters sensorimotor gating deficits induced by dopaminergic activation Psychoneuroendocrinology · 2011 · 53 citations
    10. Inhibition of 5α‐Reductase Activity in Late Pregnancy Decreases Gestational Length and Fecundity and Impairs Object Memory and Central Progestogen Milieu of Juvenile Rat Offspring Journal of Neuroendocrinology · 2011 · 32 citations
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