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    Glossary Prefrontal Cortex

    region of the brain responsible for decision-making and social behavior

    The prefrontal cortex (PFC) is the front part of the brain's frontal lobes, located just behind the forehead. It is crucial for complex cognitive behaviors such as decision-making, problem-solving, and controlling social behavior. The PFC is also involved in personality expression and moderating social conduct, making it essential for planning and executing tasks.

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    Research 30 of 204

    1. Restricted effects of androgens on glucocorticoid signaling in the mouse prefrontal cortex and midbrain Frontiers in Endocrinology · 2024 · 3 citations
    2. Pregnancy's lasting imprint: Late pregnancy allopregnanolone alters rat fear recall and medial prefrontal cortex activity Hormones and Behavior · 2026
    3. Detection of circular RNA expression and related quantitative trait loci in the human dorsolateral prefrontal cortex Genome Biology · 2019 · 48 citations
    4. Prefrontal 5α-reductase 2 mediates male-specific acute stress response Science Advances · 2025 · 5 citations
    5. Dietary glucoraphanin prevents the onset of psychosis in the adult offspring after maternal immune activation Scientific reports · 2018 · 36 citations
    6. Hedonic sensitivity to natural rewards is affected by prenatal stress in a sex-dependent manner Addiction Biology · 2015 · 28 citations
    7. The Neurosteroidogenic Enzyme 5α-Reductase Mediates Psychotic-Like Complications of Sleep Deprivation Neuropsychopharmacology · 2017 · 27 citations
    8. Acetate meliorates depressive-like behaviour in a rat model of PCOS through suppression of HDAC2 expression and DNA methylation Research Square (Research Square) · 2022 · 1 citations
    9. Inhibition of 5α-reductase in the nucleus accumbens counters sensorimotor gating deficits induced by dopaminergic activation Psychoneuroendocrinology · 2011 · 53 citations
    10. Inhibition of 5α‐Reductase Activity in Late Pregnancy Decreases Gestational Length and Fecundity and Impairs Object Memory and Central Progestogen Milieu of Juvenile Rat Offspring Journal of Neuroendocrinology · 2011 · 32 citations
    11. Depletion of cortical allopregnanolone potentiates stress-induced increase in cortical dopamine output Brain Research · 2002 · 52 citations
    12. 1. 2年間の低負荷レジスタンストレーニングが高齢者の筋機能に及ぼす効果(第134回日本体力医学会関東地方会) 体力科學 · 2005
    13. Isolation rearing-induced reduction of brain 5α-reductase expression: Relevance to dopaminergic impairments Neuropharmacology · 2011 · 48 citations
    14. Anabolic–Androgenic Steroids and Brain Damage: A Review of Evidence and Medico-Legal Implications Forensic Sciences · 2025 · 2 citations
    15. Allopregnanolone mediates the exacerbation of Tourette-like responses by acute stress in mouse models Scientific reports · 2017 · 25 citations
    16. The anxiolytic-like effects of estazolam on a PTSD animal model Psychiatry research · 2018 · 12 citations
    17. Effects of Restraint Stress and Allopregnanolone Inhibition on Amphetamine Locomotor Sensitivity Digital Scholarship - UNLV (University of Nevada Reno) · 2013 · 1 citations
    18. Measuring Finasteride Efficacy Dermatology · 2003 · 1 citations
    19. Effects of non-contingent cocaine on 3alpha-androstanediol. I. Disruption of male sexual behavior Physiology & Behavior · 2019 · 4 citations
    20. Allopregnanolone in the bed nucleus of the stria terminalis modulates contextual fear in rats Frontiers in Behavioral Neuroscience · 2015 · 34 citations
    21. Sex Differences in Animal Models of Sodium-Valproate-Induced Autism in Postnatal BALB/c Mice: Whole-Brain Histoarchitecture and 5-HT2A Receptor Biomarker Evidence Biology · 2022 · 9 citations
    22. Exploring the Impact of the Microbiome on Neuroactive Steroid Levels in Germ-Free Animals International journal of molecular sciences · 2021 · 11 citations
    23. Novel Synthetic Steroid Derivatives: Target Prediction and Biological Evaluation of Antiandrogenic Activity Current Issues in Molecular Biology · 2025
    24. Red Light Revolution: Harnessing Photobiomodulation for Peak Athletic Performance and Systemic Healing Quality in Sport · 2026
    25. Barbering in Laboratory Rodents: Problems and Prospects Российский физиологический журнал им  И  М  Сеченова · 2024
    26. Sex differences in the hypothalamic–pituitary–adrenal axis’ response to stress: an important role for gonadal hormones Neuropsychopharmacology · 2019 · 197 citations
    27. Ferulic acid inhibits catamenial epilepsy through modulation of female hormones Metabolic Brain Disease · 2022
    28. Neuroactive Steroids and Ethanol Exposure: Relevance to Ethanol Sensitivity and Alcohol Use Disorders Risk Elsevier eBooks · 2019 · 1 citations
    29. Exome-wide age-of-onset analysis reveals exonic variants in ERN1 and SPPL2C associated with Alzheimer’s disease Translational Psychiatry · 2021 · 12 citations
    30. The nocebo effect: A clinicians guide Australian and New Zealand Journal of Psychiatry · 2012 · 41 citations