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Mutations in the enzyme don't significantly change how it binds to its specific substances.

Oral zinc sulphate is an effective and safe treatment for thallium poisoning, especially for skin and hair symptoms.

Dorper sheep's wool shedding is linked to specific genes and pathways, which may help understand human hair growth.

People with alopecia areata often have lower iron levels than healthy people.

Modern hair care trends often reinvent old practices to create new trends or reinforce existing ones.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Human hair keratins can self-assemble and support cell growth, useful for biomedical applications.

Children need early diagnosis and treatment for iron-deficiency anemia to prevent learning problems and promote health.

Some breast cancer treatments caused long-term hair loss in women, similar to a condition called alopecia areata.

A woman with severe hair loss due to systemic sclerosis regrew her hair in 4 months using a combination of treatments.

Oral zinc sulphate is an effective and safe treatment for thallium poisoning.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

Human skin can make serotonin and melatonin.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

Melatonin may benefit skin health and could be a promising treatment in dermatology.