14 citations
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May 2008 in “Journal of Visualized Experiments” This article details a protocol for isolating and culturing embryonic neural crest stem cells from the whisker follicles of adult mice.
2 citations
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June 2023 in “Clinical Cosmetic and Investigational Dermatology” In this study, post-treatment with DCO was found to speed up epidermal wound healing after micro-needling of 3D skin models while maintaining the treatment's immunostimulatory benefits, potentially optimizing aftercare and reducing patient recovery time.
9 citations
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February 2025 in “Biomimetics” This study highlights the potential benefits and current limitations of robotic systems in nipple-sparing mastectomies, noting their promise in reducing surgeon fatigue but pointing out challenges such as longer operating times, high costs, and limited haptic feedback.
5 citations
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July 2022 in “Frontiers in Medicine” In this study, the combination of ECM-C with microneedle and radiofrequency treatments improved periorbital wrinkles, skin elasticity, and thickness more effectively than ECM-C with microneedles alone, but subjective evaluations showed no significant differences.
January 2024 in “Journal of Cutaneous and Aesthetic Surgery” This study describes a method to safely guard needles used in comedone extraction and scalp procedures during hair transplantation, aiming to prevent deep injuries and reduce patient fear.
7 citations
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July 2022 in “Pharmaceutics” This study found that a dissolvable microneedle device delivering rapamycin and epigallocatechin gallate nanoparticles significantly enhanced hair regrowth in C57BL/6 mice within 7 days, demonstrating increased hair shaft growth and follicle density with minimal inflammation compared to untreated mice.
February 2023 in “Molecules” In this study, N. ottonis cactus cell extract applied to mice promoted hair growth and increased the number of hair follicles, suggesting its potential as a hair-growth-promoting agent.
8 citations
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August 2020 in “PLOS Computational Biology” This study presents a computational approach, CATNIP, which repurposes drugs using only their biological and chemical information, predicting new uses like adrenergic uptake inhibitors for Parkinson's and vandetanib for Type 2 Diabetes.
March 2022 in “Clinical Cosmetic and Investigational Dermatology” This study identified altered mRNA and lncRNA profiles in NS scalp tissues, highlighting CDKN2AIP as a downregulated gene involved in a ceRNA network.
This abstract discusses the mechanism and effects of ablative carbon dioxide laser treatment for skin tightening, reporting no new clinical results but noting the need for involved postoperative management.
40 citations
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March 2019 in “Pharmaceutical development and technology” The study found that cyproterone acetate-loaded nanostructured lipid carriers, particularly those with a 300 nm diameter, improved skin penetration and targeted hair follicles more effectively than free cyproterone acetate.
9 citations
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November 2024 in “Journal of Wound Management Official journal of the European Wound Management Association” Cold Plasma shows promise for healing wounds by killing bacteria and helping tissue grow.
October 2023 in “Applied materials today” In this study, researchers developed a novel TA-encapsulated microneedle applicator that successfully promoted hair growth and reduced inflammation in a C3H/HeJ mouse model of alopecia areata, potentially offering an improved alternative to existing treatments.
January 2026 in “Updates in clinical dermatology” 7 citations
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June 2017 in “The Journal of Dermatology” This abstract notes a disclaimer about supporting information and does not report new research findings.
September 2021 in “CRC Press eBooks” This article discusses features, genetics, and diagnostic challenges of central centrifugal cicatricial alopecia in African American women but reports no new clinical results.
July 2024 in “The journal of investigative dermatology/Journal of investigative dermatology” In a pilot study with 21 patients, the niostem device increased hair counts and density and enhanced testers’ self-perception of hair growth at 6 months without reported adverse effects, suggesting potential benefits for androgenetic alopecia.
August 2023 in “Chinese Journal of Dermatology” This review reports that studies from China and elsewhere indicate microneedling, combined with traditional therapies, enhances treatment outcomes for androgenetic alopecia, offering superior efficacy, a shorter treatment period, and improved safety compared to conventional methods.
May 2026 in “IOSR Journal of Dental and Medical Sciences” This study evaluated the use of automated microneedling therapy for managing facial scars, finding significant improvement in scar size and vascularity with minimal complications, particularly between the second and third treatment sessions, and achieving good to excellent patient satisfaction in two-thirds of participants.
61 citations
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April 2023 in “Bioactive Materials” This review article highlights recent advances in microneedle technology for wound healing and tissue regeneration, discussing various cargo types, structural designs, and fabrication methods, and suggesting guidelines for designing microneedle systems tailored to specific applications.
2 citations
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March 2024 in “Pharmaceutics” This study demonstrated that while the proposed placebo microneedle stamp design was partially successful in blinding participants with low skin sensitivity, further development of suitable placebo controls is needed.
75 citations
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March 2009 in “Journal of The American Academy of Dermatology” This review discusses the evolution and ongoing debate about the causes of central centrifugal cicatricial alopecia in African American women, without presenting new clinical findings.
41 citations
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August 2024 in “Drug Delivery and Translational Research” This review discusses the development and applications of microneedles, particularly through 3D printing, highlighting their potential in transdermal drug delivery but reporting no new results.
26 citations
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April 2011 in “Skin Research and Technology” This study found that in vivo confocal scanning laser microscopy accurately quantifies neogenic hair follicles in mice, producing results similar to histology while avoiding fixation artifacts.
1 citations
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October 2025 in “Micromachines” This review highlights the potential of integrating point-of-care testing with allele-specific amplification techniques like AS-PCR, AS-LAMP, and AS-RPA to improve the efficiency, accuracy, and affordability of genotyping single nucleotide polymorphisms associated with human diseases.
2 citations
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June 2025 in “ACS Biomaterials Science & Engineering” This study demonstrates that encapsulating cell-free fat extract in a gelatin methacrylate hydrogel enhances flap repair by sustaining angiogenesis, reducing oxidative stress, and offering favorable biocompatibility in a murine skin flap model, thereby advancing potential clinical flap necrosis treatments.
11 citations
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June 2020 in “Journal of cosmetic dermatology” In this study, a home-use microneedle device combined with 5% minoxidil showed potential for enhancing hair growth in pattern hair loss over six months, although the observed improvements in hair count and patient assessments were not statistically significant compared to other treatments.
5 citations
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September 2024 in “International Journal of Molecular Sciences” This study used a 3D bioprinted human lung cancer model in a mouse phantom to demonstrate a selective cytotoxic effect of X-rays on tumor cells, revealing differences from 2D cell models.
January 2025 in “Dermatological Reviews” This study reports that Cyperus rotundus L. (nut grass) shows promise as a natural hair removal agent, with compounds targeting hair follicles and potentially offering an alternative to chemical depilatories, demonstrated by its efficacy in clinical trials and comparable results to some laser treatments.
81 citations
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July 2011 in “Lasers in Medical Science” This study found that using a low-level laser comb led to hair regrowth in a mouse model of alopecia areata, while sham-treated mice showed no hair regrowth.