1 citations
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November 2023 in “Journal of ovarian research” In this study involving rats with letrozole-induced polycystic ovary syndrome, Agaricus subrufescens significantly reduced blood glucose, total cholesterol, testosterone levels, and renal markers, suggesting its potential protective effects on both metabolic and reproductive parameters.
This review discusses the complexities of managing polycystic ovarian syndrome in females, examining its various phenotypes and treatment options, but it does not present new clinical findings.
This article discusses the impact of hyperandrogenism in polycystic ovary syndrome on women's physical and mental health, but it reports no new experimental findings.
August 2020 in “Current psychopharmacology” In this study, neurotrophic factors, synaptic plasticity, and neurogenesis changed in the hippocampus of rats during pregnancy, lactation, and pup deprivation, potentially influencing maternal care.
343 citations
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December 2008 in “Endocrine Reviews” This review discusses the various evidence-based and potential applications of metformin in treating and preventing symptoms and complications associated with polycystic ovary syndrome but reports no new clinical results.
92 citations
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May 2014 in “The American Journal of Medicine” This review discusses the multi-system impacts of polycystic ovary syndrome and explores evaluation and treatment strategies, but it reports no new research findings.
87 citations
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July 2018 in “Nursing Clinics of North America” This review discusses the diagnostic criteria and treatment options for polycystic ovary syndrome focusing on metabolic subtypes and reports no clinical results.
54 citations
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August 2017 in “Gynecological Endocrinology” This review discusses treatments for polycystic ovary syndrome, including lifestyle changes, oral contraceptives, and various medications, and reports no new clinical findings; the authors highlight the potential of statins and inositol for managing symptoms.
48 citations
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May 2012 in “Journal of Midwifery & Women's Health” This review discusses the symptoms, diagnosis, and current treatment recommendations for polycystic ovary syndrome, noting that many women may remain undiagnosed and at risk for complications.
42 citations
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January 2024 in “Frontiers in Endocrinology” This review discusses polycystic ovary syndrome treatments, focusing on the potential benefits and safety of herbs and phytochemicals, and reports no new clinical results.
40 citations
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January 2010 in “Annales D Endocrinologie” This article discusses diagnostic guidelines for PCOS, emphasizing the use of the Rotterdam criteria and recommending clomiphene citrate as the first-line treatment for ovulation induction; it reports no new clinical results.
39 citations
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January 2019 in “The World Journal of Men's Health” Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.
27 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This article explores the endocrine functions involved in the pathogenesis of polycystic ovarian syndrome and discusses approaches for diagnosing and managing the condition, with no new clinical results reported.
26 citations
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July 2021 in “International journal of adolescent medicine and health” This review covers various treatments for managing PCOS symptoms and infertility, noting that aromatase inhibitors may be as or more effective than clomiphene citrate for ovulation induction but reports no new clinical results.
26 citations
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January 2016 in “Indian journal of endocrinology and metabolism” In this randomized trial, metformin and pioglitazone both improved certain clinical and metabolic indices in women with PCOS, with pioglitazone showing potential as an alternate treatment for those intolerant to metformin.
25 citations
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June 2012 in “Endocrine” This review discusses emerging concepts in PCOS from the AEPCOS 2010 meeting and reports no clinical findings; it suggests that the transition of care in congenital adrenal hyperplasia could inform PCOS adolescent care.
24 citations
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May 1985 in “The Journal of Clinical Endocrinology & Metabolism” In this case study, the authors identified a circulating low molecular weight inhibitor that may contribute to insulin resistance in a woman with acanthosis nigricans and polycystic ovary syndrome.
23 citations
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June 1997 in “Baillière's clinical obstetrics and gynaecology” This article discusses various diagnostic categories and treatments for hyperandrogenism, with a focus on polycystic ovary syndrome and reports no new clinical findings, calling for specific treatments and lifestyle changes.
21 citations
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November 2017 in “Cochrane library” This study concluded that laparoscopic ovarian drilling does not clearly improve menstrual regularity or androgenic symptoms in PCOS compared to most medical treatments, but it may have fewer gastrointestinal side effects than metformin plus clomiphene.
19 citations
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October 2012 in “Frontiers of Hormone Research” This article reviews treatment strategies for ovulation induction in women with PCOS seeking pregnancy, emphasizing lifestyle changes and pharmacological options, and reports no new clinical findings.
18 citations
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December 2014 in “Obstetrics and Gynecology Clinics of North America” This study suggests that weight loss can improve fertility outcomes in overweight and obese women with PCOS, and letrozole should be considered the new first-line treatment over clomiphene citrate for anovulatory infertility in this population.
18 citations
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March 2014 in “Current Pharmaceutical Biotechnology” This review discusses metformin's use in women with polycystic ovary syndrome, focusing on benefits during pre-conception and pregnancy, but reports no new clinical results.
17 citations
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February 2004 in “PubMed” This review discusses symptom-driven treatment approaches for PCOS, focusing on ovulation induction, androgen reduction, and weight management, and reports recent advances like recombinant FSH and GnRH-agonist protocols without providing new clinical results.
16 citations
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January 2007 in “Journal of Obstetrics and Gynaecology” This article provides a comprehensive overview of polycystic ovary syndrome, its diagnosis, complications, and symptom-focused management options, but does not present new clinical findings.
13 citations
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October 2011 in “Clinical Obstetrics and Gynecology” This review covers the diagnosis of polycystic ovary syndrome and the management of related infertility, describing evaluation and initial treatment steps, without presenting new clinical results.
12 citations
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October 2004 in “Expert Opinion on Investigational Drugs” This review discusses current and emerging therapeutic strategies for managing polycystic ovary syndrome, emphasizing treatment tailored to individual patient complaints and highlighting the roles of hormone therapy and insulin-sensitizing agents.
11 citations
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July 2003 in “The Nurse practitioner” This article reviews diagnostic and management strategies for polycystic ovary syndrome in primary care and reports no new clinical results; it also discusses when specialist referral is appropriate.
10 citations
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January 2019 in “The Nurse Practitioner” This article reviews diagnostic and treatment guidelines for polycystic ovary syndrome, discussing how nurse practitioners can enhance patients' quality of life through education; it reports no new clinical results.
10 citations
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November 2010 in “Journal of Pharmacy Practice” This article discusses polycystic ovary syndrome, highlighting treatment approaches for managing insulin resistance, hyperandrogenism, and fertility issues, but reports no new clinical results.
10 citations
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June 2006 in “Fertility and Sterility” This article discusses the diverse symptoms and treatment options for polycystic ovary syndrome, emphasizing diligent management of its metabolic component, but reports no new findings.