60 citations
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February 2010 in “Gynecological Endocrinology” This study suggests that adding metformin to diet and exercise improves insulin resistance and hyperandrogenism in women with PCOS, though lifestyle changes alone may enhance menstrual cycles.
45 citations
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January 2018 in “International Journal of Dermatology” This review explores nail changes associated with alopecia areata, noting their prevalence and impact on appearance and function, but reports no new clinical findings; the authors call for larger controlled trials.
30 citations
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March 2001 in “Environmental Health Perspectives” This review explores the significant impacts of hormonal changes within normal physiological ranges and suggests examining low-dose effects from chemicals disrupting hormonal activity; it presents no new clinical results.
19 citations
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January 2018 Most people with alopecia areata have nail changes, which are common but don't greatly affect their quality of life.
13 citations
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December 2001 in “Dermatologic therapy” This review discusses the clinical presentations of alopecia areata, introduces guidelines for treatment studies, and explores potential changes in cutaneous innervation, but reports no new clinical results.
3 citations
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June 1981 in “PubMed” This article reviews the skin changes that can occur with hormonal contraceptive use and highlights various mechanisms and potential treatment strategies but reports no new clinical results.
2 citations
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August 2015 in “Journal of dermatology” This letter to the editor reports a case of alopecia universalis occurring alongside minimal change nephrotic syndrome, but it presents no new clinical findings.
1 citations
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May 2025 in “BMC Veterinary Research” This research highlights the importance of considering hypothyroidism in dogs for early diagnosis and treatment to prevent potentially life-threatening complications, given its relative commonality compared to other diseases causing dermatological changes or obesity in these animals.
January 2026 in “Journal of Ayurveda and Integrated Medical Sciences” In this case study, a 20-year-old female with hypothyroidism experienced marked symptom improvement, including weight reduction and menstrual regularization, after Ayurvedic management involving herbal remedies and lifestyle changes, suggesting Ayurveda could complement conventional therapies and indicating the need for larger-scale validation.
January 2026 in “Veterinarski glasnik” In this case report, researchers highlighted the importance of age-appropriate interpretation of clinical findings in an orphaned Bosnian Mountain Horse foal, observing that physiological changes rather than pathological ones contributed to variations in blood and biochemical parameters, while also diagnosing skin lesions of distinct origins.
September 2025 in “Clinical Cosmetic and Investigational Dermatology” In this randomized, placebo-controlled study, Kūlaris supplementation significantly improved quality of life for participants with mild-to-severe acne over 12 weeks, though no significant changes in general skin health measures were observed compared to placebo.
February 2025 in “Archives of Dermatological Research” This study found that combining microneedling with 5% Minoxidil and Finasteride significantly improved hair density and hair shaft diameter in males with androgenetic alopecia, outperforming Minoxidil alone or in combination with Finasteride, although changes in hormonal levels and trace elements were not significant.
September 2024 in “Journal of the American Academy of Dermatology” Seborrheic dermatitis affects quality of life and sleep, linked to stress and nervous system changes.
October 2023 in “Journal of The American Academy of Dermatology” This article discusses the use of low-dose oral minoxidil as an off-label treatment for androgenetic alopecia but reports no new clinical results.
February 2022 in “Endocrine connections” This review summarizes existing research on how various endocrinopathies, including reproductive disorders and thyroid conditions, can affect vocal parameters, and reports no new clinical findings.
January 2021 in “Veterinary research forum” In this study of a Holstein calf with severe congenital ichthyosis, researchers found increased plasma parameters and specific skin changes, highlighting the genetic and incurable nature of this disease in livestock.
November 2016 in “Journal of Evolution of Medical and Dental Sciences” This study observed that among elderly patients, the most common systemic disease associated with skin conditions was diabetes, while wrinkling and xerosis were prevalent skin changes.
January 2016 in “Journal of Investigative Dermatology” Some cells may slow melanoma growth, a protein could affect skin pigmentation, a gene-silencing method might treat hair defects, skin bacteria changes likely result from eczema, and a defensin protein could help treat multiple sclerosis.
In this prospective observational study, researchers observed that hyperthyroidism significantly affects cardiac function, often resulting in reversible cardiac changes, with echocardiography playing a crucial role in diagnosis and monitoring.
March 2012 in “Journal of Pediatric and Adolescent Gynecology” This study found significant variability among NASPAG members in diagnostic approaches for PCOS, though there was more agreement on recommended first-line therapies such as oral contraceptives and lifestyle changes.
15 citations
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May 2021 in “International Journal of Dermatology” This review examines the links between climate change, migration, and skin diseases and calls for global strategies to improve migrant health but reports no new clinical results.
141 citations
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January 1984 in “Journal of The American Academy of Dermatology” This review discusses skin changes during pregnancy, highlighting both pregnancy-specific and common physiologic changes, but reports no new clinical findings.
43 citations
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November 2007 in “Dermatologic Clinics” This article discusses various hair and nail abnormalities linked to paraneoplastic conditions and cancer treatments, emphasizing their potential role in diagnosing and managing internal malignancies and reports no new clinical findings.
36 citations
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November 2016 in “European journal of dermatology/EJD. European journal of dermatology” This review examines systemic drugs that can cause changes in hair color and emphasizes the importance of reporting these adverse events, but it does not include new clinical outcomes.
32 citations
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January 2007 in “KARGER eBooks” This review discusses severe insulin resistance syndromes, highlighting their diagnostic challenges, potential novel therapies like leptin replacement, and suggests metformin and lifestyle changes in its absence; no new clinical results are reported.
26 citations
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January 2020 in “Przegląd Menopauzalny” This review discusses the role of androgens in menopausal women's health, highlighting symptoms of both hyperandrogenemia and androgen deficiency, but reports no clinical results.
June 2025 in “Frontiers in Immunology” This study reported that anti-Ku-positive patients exhibited heterogeneous muscular features, primarily characterized by necrotizing fibers and vacuolar changes, and suggested that autophagy could be a significant mechanism involved in the pathogenesis.
This study highlights the complexity of diagnosing scalp fungal infections, emphasizing how clinical evaluation, trichoscopy, and cultural samples are essential in distinguishing tinea capitis from similar conditions like piedra, seborrheic dermatitis, and psoriasis, due to overlapping symptoms like scaling and hair changes.
January 2023 in “Zdravstvena zaštita” This review evaluates current research on how hormonal changes due to aging impact voice quality, concluding the vocal cords are sensitive to hormonal fluctuations throughout life but reports no new clinical results.
July 2020 in “International Journal of Dermatology Venereology and Leprosy Sciences” In this study, dermatological changes were highly prevalent among postmenopausal women, with xerosis, pigmentary changes, and hair thinning being the most common findings, suggesting such changes are often overlooked in clinical practice.