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Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

New topical antifungals and delivery systems are improving treatment for fungal skin infections, but patient education and prevention are key.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.

Minoxidil helps heart function but doesn't improve exercise ability and may cause complications.

Microneedling is promising for treating various skin issues but needs more research to confirm its effectiveness and safety.

PLD is an effective and safer alternative for treating breast cancer.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

Thymus transplantation successfully restored immune function in infants with FOXN1 deficiency.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

Voriconazole can cause serious side effects, especially in long-term use.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.

Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.

Hair follicles greatly increase caffeine absorption through the skin shortly after it's applied.

Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.