Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

The study found that bioengineered hair follicles work when using cells from the same species but have issues when combining human and mouse cells.

This review discusses cellular plasticity in skin and intestine, hypothesizing that mature cell reprogramming might contribute to tumorigenesis, and reports no new clinical results.

This study found that active androgens activate lipogenic differentiation in human sebocytes expressing a functional androgen receptor, influencing gene expression and lipid synthesis, while also increasing apoptotic cell population over time.

This clinical case study describes an aggressive squamous cell carcinoma developing within a giant epidermal cyst on the abdomen.

This study demonstrated that bioluminescence imaging of NG2+ cells in transgenic rats allows in vivo monitoring of hair follicle cycles to study hair growth and follicle regeneration.

This study examined the expression patterns of various cytokeratins in the outer root sheath of human anagen hair follicles, noting distinct differentiation patterns and localization of keratin markers.

This review found that while MSC and EV-based therapies could potentially improve skin and hair rejuvenation, their clinical efficacy is limited by inconsistent study designs and a lack of standardization.

This review systematically assembles recent insights into the use of hair follicle neural crest stem cells and their exosomes for peripheral nerve injury repair, highlighting molecular mechanisms and possible translational applications, with comprehensive tables and diagrams summarizing existing literature.

This study found that exosomes derived from dental pulp mesenchymal stem cells (DPSC-Exos) significantly promoted hair regrowth and follicle density in a mouse model of androgenetic alopecia, showing similar efficacy to minoxidil by activating pathways that improve follicular vascularization and dermal papilla cell function.

This systematic review found an increased incidence of hair loss and telogen effluvium among COVID-19 patients and reported preliminary effectiveness of platelet-rich plasma, adipose-derived mesenchymal stem cells, and human follicle stem cells for treatment without major side effects.

This study found that reconstructed human epidermis from infant skin is more susceptible to UV damage than that from older children, with notable changes in skin cell characteristics during the early years of life.

This study observed that nevus melanocytes do not exhibit signs of senescence, suggesting that their growth arrest is due to cell interactions and not directly caused by BRAF activation.

This study successfully optimized a culture strategy for dermal papilla cells and established an immortalized cell strain, iDP6, which closely resembles primary DP cells in key characteristics.

In this study, RNA-Seq analysis identified 2717 genes differentially expressed between anagen and telogen hair follicle stem cells in cashmere goats, potentially involving several signaling pathways in vitro.

This study found that mesenchymal cell processes from the dermal papilla contact epithelial hair matrix cells through gaps in the basal lamina during hair matrix cell differentiation in mouse vibrissa follicles.

This study found that recombinant human leukocyte interferon alfa-2a achieved a 64% overall antitumor response rate in patients with early and advanced cutaneous T cell lymphoma and was generally well-tolerated.

This review explores the role of regulatory T cells in autoimmune skin disorders like alopecia areata and vitiligo, emphasizing unanswered questions and reporting no new experimental results.

In this study, 1,25-dihydroxyvitamin D3 inhibited growth and promoted differentiation in normal hair follicle cells but did not affect cells from a patient with vitamin D-dependent rickets type II, assisting in potential rapid diagnosis of the condition.

This study found that skin-resident and recruited γδ T cells play a crucial role in an early wound healing response following cutaneous vaccinia virus infection, rather than in controlling virus replication.

This review examines the diversity and role of stem cells in the adult dermis, noting a lack of precise understanding about their hierarchy and relationship to dermal fibroblast subpopulations, and reports no new results.

This study found that androgenic alopecia was associated with a decreased risk of testicular germ cell tumors but a potential increased risk of high-grade prostate cancer.

This study found that trichohyalin is expressed in cancerous tongue epithelial cells, while plectin-1 expression may indicate malignancy.

In this study, researchers developed a sensitive assay to measure the inhibition of steroid 5-α reductase (5AR) by chemicals like finasteride and dutasteride, revealing species-specific differences in inhibitor efficacy between human and fish cell lines.

This review discusses the cytotoxic effects of various selenium compounds on human mammary tumor cells and explores the impact of selenium and magnesium in dietary studies with nude mice, reporting no new clinical results.

This study demonstrated that cryogelation of human hair keratin allows the development of 3D scaffolds with tunable properties, supporting cell adhesion and proliferation for potential biomedical applications.

This case report describes a 42-year-old male with alopecia areata and a scalp neurofibroma, emphasizing the tumor's histopathological features and the patient's decision against surgical treatment.

This chapter describes the functions and purposes of hair care cosmetics, including shampoos, hair growth promoters, and grooming products, without reporting new experimental findings.

This article reviews the distinctive features of cutaneous lymphadenoma, a variant of trichoblastoma, and its differential diagnosis, but it presents no new empirical results.

This case report describes a 30-year-old woman with vitiligo who developed a rare dermatophyte infection encircling one of her vitiligo patches, possibly due to immunosuppression from her treatment.

This article reviews historical reports of skin changes, such as pseudoacanthosis nigricans, associated with cholesterol-lowering drugs like triparanol and nicotinic acid, but presents no new clinical findings.