Diffuse Neurofibroma of the Scalp with Alopecia Areata as the Initial Presentation: A Case Report

January 2014 in “ International Journal of Dermatology and Venereology ”

Xiulian Xu, Xuebao Shao, Xuesi Zeng, Jianfang Sun

alopecia areata diffuse neurofibroma scalp swelling S-100 protein dermis subcutaneous tissue spindle cells myxoid matrix collagen fibers mast cells

TLDR A man with hair loss and a scalp lump was diagnosed with a diffuse neurofibroma but chose not to have surgery.

A 42-year-old male presented with alopecia areata and a scalp swelling, which was diagnosed as a diffuse neurofibroma. The mass, measuring 10 cm × 8 cm, was located on the left scalp and had a 'bag of worms' texture. Histopathological examination revealed an infiltrative mass in the dermis and subcutaneous tissue, composed of spindle cells, myxoid matrix, collagen fibers, and mast cells, with 50% of the tumor cells expressing S-100 protein. Despite the diagnosis, the patient declined surgical treatment due to the extensive involvement of the head, and was instead monitored through follow-up.

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community 25M Exploring Causes of Hair Loss: TE, Alopecia, or AGA?

in General 226 upvotes 2 months ago

The user is experiencing hair loss with possible causes including chronic telogen effluvium, diffuse alopecia areata, and androgenic alopecia. They have tried treatments like Nizoral shampoo, minoxidil, and finasteride, and are considering a biopsy for further clarity.

community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 3 years ago

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community Boys I am just a gonner. What on earth is my scalp even going through. Looks like world war 3. Pyril 3 months. Topical melitonin/progesterone/fin, dut, fin, oral min, laser trash, anus stimulation. Nothing. Donor area is decimated 😂.

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community Female, 27 years old, shedding/ balding despite being on what is considered to be a effective treatment plan for AGA. Considering Dut (oral) . Please help.

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community Seeking Advice: Unusual Hair Loss at 31 Years Old - Any Insights? (M)

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community Saw a local dermatologist recently, they suggested switching from Finasteride to Dutasteride…

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