160 citations
,
January 2009 in “Clinical Drug Investigation” This study found that the HairMax LaserComb® significantly increased hair density and was safe and well tolerated for treating androgenetic alopecia in men compared to a sham device.
2 citations
,
January 2018 in “Recent clinical techniques, results, and research in wounds” This review discusses the effects of low-level laser therapy in various biological processes for wound healing and tissue repair and reports no new results.
This study found significant cephalometric changes in patients with skeletal Class III malocclusion treated with rapid maxillary expansion and reverse traction, demonstrating maxilla advancement and improved facial convexity.
This study found that in a rat model of alopecia, combining low-level laser therapy with Neoptide treatment resulted in better hair regrowth compared to either treatment used alone.
1057 citations
,
November 2011 in “Annals of Biomedical Engineering” This review discusses the applications of low level laser therapy (LLLT) in wound healing, pain reduction, and treating various conditions, but reports no new clinical results; the authors highlight the need for randomized controlled trials for serious diseases.
81 citations
,
August 2014 in “Lasers in Surgery and Medicine” This study found that low-level laser therapy significantly increased hair growth in women with androgenic alopecia, achieving a 37% greater increase in hair counts compared to placebo.
10 citations
,
August 2018 in “Dermatologic Surgery” This study found that 1,550-nm Er:Glass fractional laser treatment increased hair density and shaft diameter in patients with androgenetic alopecia, but did not up-regulate Wnt10A and IGF-1 mRNA expression.
81 citations
,
July 2011 in “Lasers in Medical Science” This study found that using a low-level laser comb led to hair regrowth in a mouse model of alopecia areata, while sham-treated mice showed no hair regrowth.
31 citations
,
October 2012 in “Archives of ophthalmology” Laser hair reduction near the eyebrows can cause serious eye injuries even with safety measures.
24 citations
,
November 2021 in “PLoS ONE” In this study, fractional laser treatment was observed to reverse age-related gene expression changes in skin and enhance dermal remodeling, further improved by multiple treatments.
7 citations
,
June 2019 in “Cureus” This literature review suggests that fractional lasers and microneedling, particularly when used with topical agents, may be effective treatments for alopecia areata; however, the small size and number of studies highlight a need for larger trials to confirm efficacy.
5 citations
,
April 2019 in “Plastic and reconstructive surgery. Global open” This literature review suggests that fractional laser therapies may positively impact hair regrowth in androgenic alopecia, though current evidence is mostly limited to small studies and case reports, highlighting a need for more comprehensive randomized controlled trials to confirm their efficacy and safety.
3 citations
,
September 2024 in “BMC Oral Health” This study found that low-level laser therapy effectively reduced relapse rates, while functional appliances did not; combining them offered no additional benefits.
45 citations
,
December 2018 in “Lasers in Medical Science” In a 24-week randomized trial, this study found that the RAMACAP laser helmet significantly increased hair density and diameter in androgenetic alopecia patients compared to a sham device, although limitations included a small sample size and potential issues with the control used.
24 citations
,
March 2015 in “Dermatologic Surgery” This review discusses the modest efficacy of home-use laser and light devices for conditions like hair removal and acne, noting limited evidence and a lack of robust trials.
5 citations
,
January 2021 in “Veterinary dermatology” This study found that adding low-level laser therapy to conventional treatment for canine acral lick dermatitis significantly increased hair growth compared to conventional therapy alone, but did not significantly reduce licking behavior.
January 2020 in “Acta Scientiae Veterinariae” In this case report, a combination of ozone therapy, low-level laser, and herbal medicine gel effectively improved healing in a dog with chronic bite wounds.
This study found that both finasteride and low level laser therapy were similarly effective in improving hair regrowth for frontal pattern hair loss in men and women over a 3-month period.
52 citations
,
March 2007 in “Dermatologic Therapy” This article describes the development and validation of a standardized instrument for measuring skin involvement in cutaneous lupus erythematosus, aiming to aid future clinical research and trials.
26 citations
,
April 2011 in “Skin Research and Technology” This study found that in vivo confocal scanning laser microscopy accurately quantifies neogenic hair follicles in mice, producing results similar to histology while avoiding fixation artifacts.
15 citations
,
February 2008 in “Annals of plastic surgery” In this study, 80% of patients expressed satisfaction with diode-laser hair removal, though multiple treatments were needed for optimal results and were a deterrent for some.
6 citations
,
June 2011 in “British Journal of Dermatology” This study found that individuals with alopecia areata had significantly higher serum levels of retinol-binding protein 4 and increased IgG immunoreactivity against it, suggesting a role in the disease's pathogenesis.
4 citations
,
January 2015 in “Dermatology” This study concluded that using an erbium:YAG laser for calvarium trepanation and granulation tissue induction is comparable to the rose head burr, offering a beneficial alternative method.
September 2012 in “Medicina estética/Medicina estética” This review discusses the use of laser phototherapy for treating androgenetic alopecia and alopecia areata, highlighting the need for controlled studies to determine its efficacy.
29 citations
,
April 2019 in “Lasers in Medical Science” This study found that combining fractional erbium-glass laser therapy with topical minoxidil significantly improved hair density and diameter in men with androgenetic alopecia compared to using minoxidil alone over a 24-week period, with no serious adverse events reported.
This study observed that long-term laser hair removal in women may alter hair follicle structures and stem cell interactions, with dermal fibrosis potentially influencing hair regrowth prevention.
57 citations
,
May 2014 in “Molecular Phylogenetics and Evolution” This study utilized a sequence-structure alignment approach to improve the characterization of Class A Rhodopsin GPCR superfamily, including orphan and unclassified receptors, through evolutionary analysis.
32 citations
,
January 2010 in “Dermatology” This review discusses the combination of laser hair removal and topical eflornithine for managing resistant hirsutism, providing guidance based on existing clinical data, but reports no new results.
2 citations
,
December 2022 in “PNAS nexus” In laboratory experiments, this study found that the topical prodrug SCD-153, a derivative of 4-methyl itaconate, reduced inflammation-related gene expression and induced significant hair growth in mice, suggesting it as a promising treatment candidate for alopecia areata.
April 2023 in “Digital Library of Theses and Dissertations (Universidade de São Paulo)” This study concluded that mesenchymal stem cells from adipose tissue harvested using laser-assisted liposuction with selective photo-stimulation are as effective and low-risk for cell therapy as those obtained through conventional liposuction, based on their differentiation potential, cellular proliferation, and cytokine expression.