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Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Hair follicle regeneration needs special conditions and young cells.

Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.

HFMs can help study hair growth and test potential hair growth drugs.

Blue light promotes hair growth by interacting with specific receptors in hair follicles.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Wnt signaling is crucial for skin wound healing and reducing scars.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.

Wnt, Eda, and Shh pathways are crucial for different stages of sweat gland development in mice.

Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.

Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.