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The document concludes that the human keratin gene cluster is complex, with a need for updated naming to reflect over 50 functional genes important for hair and skin biology.

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

A gene variant in KRT71 causes the curly fur in Selkirk Rex cats.

Different combinations of human hair keratins affect how hair fibers form.

Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.

A baby girl has a hair disorder called monilethrix, causing fragile hair that may improve over time.

Sphynx cats are hairless and Devon Rex cats have curly hair due to specific genetic mutations.

The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.

Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.

Keratins are important for skin cell health and their problems can cause diseases.

Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.

The document explains the genetic causes and characteristics of inherited hair disorders.

New genetic mutations linked to rare skin disorders were found in three newborns.

Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.

KRT80 may worsen cancer by increasing growth and spread, but its full effects on treatment and outcomes need more research.

Different hair types in mammals are linked to variations in specific protein genes, with changes influenced by their living environments.

Different types of cells in the eye express specific keratins at various stages of development.

Six genetic conditions are often linked to complete scalp hair loss in children.

Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.

Two specific hair keratin genes are active during hair growth and decline as hair transitions to rest.

Hair microscopy is useful for diagnosing hair disorders, but clear definitions are needed for accurate genetic analysis.

Alopecia areata involves both innate and adaptive immunity, with specific genes linked to the disease.

A second domain of high sulfur KAP genes on chromosome 21q23 is crucial for hair structure.

The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.

Alopecia areata is caused by immune system attacks on hair follicles, often triggered by viral infections.

Researchers made a mouse model with curly hair and hair loss by editing a gene.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.