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Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.

The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."

Two specific hair keratin genes are active during hair growth and decline as hair transitions to rest.

People with Down's syndrome are more likely to have syringomas.

Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

A 44-year-old woman with Down's syndrome was diagnosed with both rheumatoid and gouty arthritis and treated with multiple medications.

Two siblings were the first reported cases of inheriting both eye coloboma and loose anagen syndrome together.

Maintaining DNA integrity in stem cells is crucial to prevent aging and cancer.

A certain mutation in the fetal alpha 5-reductase gene is linked to a higher risk of late miscarriage.

The document suggests that more research is needed to confirm if baldness can indicate a higher risk of severe COVID-19 in men.

The 595-nm pulsed dye laser effectively reduces symptoms of EFFC with minimal side effects.

A new genetic change causing early stop in the androgen receptor gene was found in a patient with androgen insensitivity syndrome.

Researchers created immortal human skin cells with constant testosterone receptor activity to study hair loss and test treatments.

Infertile men are more likely to produce sperm with abnormal chromosome numbers, which can affect pregnancy success and embryo health.

Melatonin can help prevent and treat skin damage caused by gamma rays.

Rice bran oil extracted by supercritical CO2 is considered non-genotoxic.

A patient with Rothmund-Thomson syndrome showed skin changes, hair loss, and dental defects but no cataracts or skeletal issues.

A hospital outbreak of catheter infections in calves was caused by a bacteria from a beef herd, leading to longer hospital stays, more drug use, and calf deaths.

A girl with lupus and trisomy X has a higher risk of bone problems like avascular necrosis and osteoporosis.

A man with both Klinefelter syndrome and primary hyperparathyroidism showed a rare combination of symptoms and genetic patterns.

Topical immunotherapy is the best treatment for severe alopecia areata.

A baby was diagnosed with IFAP syndrome due to a new genetic mutation, showing severe skin and developmental issues.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

DHT in the human prostate is produced through multiple pathways, not just from testosterone.

Minoxidil showed a 30% success rate for hair growth in a study, and various skin treatments were effective, but some had limitations or side effects.

Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.

The document's conclusion cannot be provided because the document is not accessible or understandable.

The document concludes that transsexual individuals often experience improved quality of life after transitioning, despite higher risks of psychiatric issues and mortality.

Different scalp and hair disorders are more common in certain ethnic groups, with the most common being androgenetic alopecia, which is treated with medications like minoxidil and finasteride.