Rheumatoid Arthritis and Gouty Arthritis in an Adult Patient with Down's Syndrome

    January 2020
    Shaima N Elgenaid, Ziryab Imad Taha Mahmoud, Mohammed Elmujtaba Adam Essa, Shahd H. A. Elwidaa, Latifa M. Elsheikh, Asaad Tageldein Idris Abdelhalim, Mustafa Mohamed Ali Hussein, Mutwaly Defealla Yousif Haron, Ayman Sati Sati Mohamed Abdelkareem Abdallah Ahmed
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    TLDR A 44-year-old woman with Down's syndrome was diagnosed with both rheumatoid and gouty arthritis and treated with multiple medications.
    This case report described a 44-year-old female with Down's syndrome who was diagnosed with both rheumatoid arthritis and gouty arthritis. She had a one-year history of joint swelling, ulnar deviation of the hands, limited motion, severe tenderness, hair loss, and scoliosis. Elevated serum uric acid, ESR, and CRP levels, along with a positive rheumatoid factor, supported the diagnosis, despite negative ANA and anti-CCP antibodies. Her treatment included hydroxychloroquine, allopurinol, baclofen, methotrexate, folic acid, and sodium valproate.
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