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GlossaryAllopurinol

medication that reduces uric acid production to treat gout

Allopurinol is a medication primarily used to treat gout and certain types of kidney stones by reducing the production of uric acid in the body. It works by inhibiting an enzyme called xanthine oxidase, which is involved in the synthesis of uric acid, thereby preventing the formation of painful urate crystals in joints and tissues.

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research Granulomatous Microscopic Colitis Due to Allopurinol

October 2015 in “The American Journal of Gastroenterology”

Allopurinol may cause rare granulomatous microscopic colitis.

research Toxic Epidermal Necrolysis

48 citations , November 1992 in “International Journal of Dermatology”

Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.

research Spontaneous Cutaneous Adverse Drug Reaction Reports: An Analysis of a 10-Year Dataset in Singapore

13 citations , March 2019 in “Pharmacology Research & Perspectives”

In Singapore, most skin reactions to drugs were in females and Chinese, often caused by painkillers, antibiotics, and some other drugs, with serious cases linked to genetics.

research Chronic Tophaceous Gout Secondary to Self-Induced Vomiting in Anorexia Nervosa

6 citations , May 2010 in “The Journal of Dermatology”

A woman with anorexia developed gout from self-induced vomiting.

research The Spectrum of Nephrocutaneous Diseases and Associations

5 citations , January 2016 in “Journal of The American Academy of Dermatology”

Skin doctors should know about skin and kidney disease links to prevent serious kidney problems.

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