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Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Chinese domestic goats have unique genetic traits due to domestication and geographic isolation.

Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.

CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.

The conclusion is that genetic testing is important for diagnosing and treating various genetic hair disorders.

Zebrafish need MYC and FGF to regenerate inner ear hair cells.

Activating Notch signaling can kill basal cell carcinoma cells.

Mice without certain skin enzymes have faster hair growth and bigger eye glands.

Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.

A protein found in safflower seeds can stimulate hair growth and speed up wound healing in mice.

Early diagnosis of Trichorhinophalangeal syndrome type 1 is crucial for treatment and was achieved through clinical examination and family history.

A new mRNA variant of the SCF gene in sheep skin produces a shorter, different protein.

Genomic research can help improve the quality and production of natural fibers in animals.

The enzymes Tet2 and Tet3 are important for skin cell development and hair growth.

A 20-year-old woman with a rare form of Turner syndrome showed improvement with hormonal therapy and needs comprehensive care.

Understanding hair growth involves complex factors, and more research is needed to improve treatments for hair loss conditions.

Epigenetic factors play a crucial role in skin health and disease.

Keeping β-catenin levels high in mammary cells disrupts their development and branching.

A new goat gene affects cashmere fiber thickness; certain variations can make the fibers coarser.

A woman with a rare hormone resistance condition also had missing teeth and hair loss, which might be new symptoms of her genetic disorder.

The document concludes that more research is needed to reduce frequent hospital visits, addiction medicine education improves with specific training, early breast cancer surgery findings are emerging, nipple smears are not very accurate, surgery for older melanoma patients doesn't extend life, a genetic condition in infants can often be treated with one drug, doctors are inconsistent with blood clot medication, a certain gene may protect against cell damage, muscle gene overexpression affects many other genes, and some mitochondrial genes are less active in mice with tumors.

The 2024 guideline updates recommendations for genetic testing, imaging, and sperm retrieval in male infertility.

CRISPR/Cas9 has improved precision and control but still faces clinical challenges.

CRISPR/Cas9 gene-editing shows promise for improving sheep and goat breeding but faces challenges with efficiency and accuracy.

Epigenetic mechanisms control skin development by regulating gene expression.

Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.

Rare genetic variants in five specific genes are linked to male-pattern hair loss but only account for a small part of the risk.

Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.