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The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

Ozone reacts more with unwashed hair, producing compounds due to scalp oils, which could lower ozone exposure but increase exposure to reaction products.

PCOS is a common hormonal disorder in women, marked by symptoms like hair growth and menstrual issues, and requires personalized treatment.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Korean Red Ginseng has beneficial components that help with stress, immunity, fatigue, memory, blood flow, and disease protection.

Skin problems are very common in people with end-stage kidney disease.

Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.

Semecarpus anacardium Linn. has many medicinal benefits.

SHBG may be a useful early indicator and treatment target for PCOS.

Hair loss links to higher death risk from diabetes and heart disease; not a direct cause, but a marker for risk factors.

*Acorus calamus* has many medicinal benefits but needs more safety research.

Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Women with PCOS often have mood disorders and a lower quality of life, and treatment should focus on both physical and mental health.

DA liposomes with chloramphenicol effectively target hair follicles and combat MRSA with minimal skin toxicity.

Certain genetic variations in the SHBG gene are linked to an increased or decreased risk of PCOS in Mediterranean women.

Severe vertex pattern hair loss may indicate a higher risk for artery plaque buildup.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.

Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.

Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.

A natural steroid in the body may protect against eye damage in glaucoma.

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.