Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review examines nonmalignant skin toxicities from immunosuppressive and transplant-related medications, emphasizing the need for effective identification and management by care providers; it presents no new research findings.

This study found that mice lacking myelin protein zero-like 3 (Mpzl3) had reduced body weight and adiposity despite increased food intake, which was linked to higher energy expenditure and improved glycemic control.

Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.

This study found that targeting SV40 T antigen expression to hair follicles in transgenic mice caused abnormal hair structure and hair loss, but did not lead to cell immortalization or tumor formation in follicles.

This review discusses the evolution of lineage-tracing strategies over the past century, emphasizing their role in identifying progenitor cells and resolving debates about cellular origins, with no new results reported.

This study found that male and female chicken feather morphology and color patterns can be extrinsically modified through molting and resetting the stem cell niche during regeneration.

In this study, researchers found that microRNAs and specific target genes, such as MiR-195 and genes like CHP1, SMAD2, FZD6, and SIAH1, play significant roles in regulating hair follicle initiation in cashmere goats.

This study identified a novel recessive mutation in mice causing lethal congenital lamellar ichthyosis, with skin and hair follicle alterations similar to human congenital ichthyoses, linked to a specific genetic defect affecting Fatp4.

This report describes a case of primary cutaneous follicle centre cell lymphoma presenting as hair thinning on the scalp, which is not a recognized feature of the condition.

This review covers various aspects of hair biology, pigmentation, and development, focusing on genetic and biochemical modulation of hair follicle components but reports no new findings.

This study demonstrated that a new non-invasive method for collecting and analyzing mouse hair follicles could replace traditional biopsy methods, providing advantages for translational research and routine applications.

This study found that the PP2A-B55α regulatory subunit is crucial for ectodermal development in mice, with knockout embryos displaying severe neural and epidermal defects and failing to survive to birth.

In this commentary, the authors discuss the challenges and proposals for responsibly translating regenerative therapies into clinical practice, emphasizing the need for patient education, quality control, and real-world evidence to validate these therapies and address ongoing misinformation in the field.

This study observed that adipose-derived stem cells modified with trichogenic factors have similar properties to dermal papilla cells and show enhanced hair regeneration potential compared to unmodified adipose-derived stem cells.

Dutasteride reduces DHT more effectively than finasteride.

This study identified a novel homozygous EDNRA variant linked to Oro-Oto-Cardiac Syndrome and showed that EDNRA signaling is essential for normal craniofacial and cardiovascular development.

In a randomized study, men treated with dutasteride for androgenetic alopecia experienced sexual adverse events at twice the rate of those on placebo during 24 weeks, but these events were mild, moderate, and resolved after treatment.

This study observed that Cyp27b1−/− mice exhibited growth and skeletal abnormalities similar to those of Vdr−/− mice, despite differences like the development of alopecia in Vdr−/− mice, suggesting that 1α,25D3 may directly influence chondrocyte proliferation and differentiation.

In this case report, a 37-year-old man with discoid lupus erythematosus experienced around 80% hair regrowth after treatment with a combination of oral and topical therapies.

In this study, subcutaneous recombinant human IL-12 showed a 43% partial response rate in early-stage mycosis fungoides patients refractory to previous treatments, with generally mild to moderate adverse events reported.

This review examines various immunomodulatory therapies for cutaneous lymphoma and notes that they are most effective in the disease's early stages.

Skin conditions can signal heart issues, highlighting the need for integrated care.

This review discusses the design and advances of lipid–polymer hybrid nanoparticles as promising delivery systems for genome editing strategies, highlighting their potential in biomedical applications.

This study found that cultured mouse dermal papilla (mDP) cells can induce hair follicle neogenesis in de novo regenerated skin tissues grafted onto mice.

This letter to the editor provides no new results or studies on dermatological topics; it may address previous articles or observations.

In this study, researchers developed a new photoactivatable Cre recombinase mouse model, DiLiCre, which allows precise light-induced genetic modifications and cell tracing, demonstrating its effectiveness for advancing biological and biomedical research.

This study found that a mutation causing Stormorken syndrome in mice led to skeletal abnormalities and unusual hair growth, showcasing the STIM1 R304W protein’s role in bone development and cell fate.

This study reports that a plant extract from Orobanche rapum can stimulate skin rejuvenation and protect cutaneous microbiota, potentially creating healthier skin.

This article discusses how challenges in drug development and success rates are driving a shift in the pharmaceutical industry towards engineering targeted drug delivery systems, with nanomaterials offering potential solutions for selective therapeutic delivery.

This case study reports on an adult with metastatic Crohn's disease treated with infliximab over 4.5 years, providing valuable follow-up data in this context.