April 2018 in “Journal of Investigative Dermatology” Nicotinic acid reduces excessive oil production in skin cells by activating a specific receptor, which could help treat acne.
April 2018 in “Journal of Investigative Dermatology” The role of γδT-cells in causing alopecia areata remains unclear.
April 2018 in “Journal of Investigative Dermatology” Acne patients' skin, both with and without lesions, shows a strong immune response and higher antimicrobial activity.
January 2018 in “Elsevier eBooks” Minoxidil helps lower severe blood pressure and promotes hair growth but can have serious side effects and must be used continuously.
November 2013 in “John Wiley & Sons, Ltd eBooks” Skin symptoms can indicate endocrine disorders and have various treatments.
January 2012 in “Elsevier eBooks” New treatments for skin and hair repair show promise, but further improvements are needed.
September 2004 in “Experimental dermatology” Melatonin directly affects mouse hair follicles and may influence hair growth.
991 citations,
January 2011 in “Nature Reviews Endocrinology” The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.
349 citations,
January 2005 in “The FASEB journal” Human skin can make serotonin and melatonin, which help protect and maintain it.
306 citations,
April 2019 in “International Journal of Molecular Sciences” The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
277 citations,
July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
228 citations,
September 2012 in “Trends in Neurosciences” Nerves are crucial for the regeneration of various body parts in many animals.
183 citations,
January 2018 in “Cosmetics” Essential oils in cosmetics can offer benefits but may cause allergies and should be used carefully.
162 citations,
July 2011 in “Biomacromolecules” Chitosan nanofiber scaffolds improve skin healing and are promising for wound treatment.
139 citations,
July 1991 in “Journal of The American Academy of Dermatology” Understanding hair follicle anatomy helps diagnose hair disorders.
133 citations,
May 2016 in “Cell Host & Microbe” Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.
124 citations,
December 2016 in “Pharmaceuticals” TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
120 citations,
February 2009 in “Apoptosis” Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
105 citations,
May 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” Activating TRPV3 stops human hair growth.
102 citations,
July 2007 in “Genes & Development” A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.
87 citations,
March 2000 in “American Journal of Clinical Dermatology” Alpha-hydroxy acids, like glycolic acid, safely improve skin issues and work on all skin types.
84 citations,
April 2013 in “Applied Microbiology and Biotechnology” Mannosylerythritol lipids are good for skin and hair care products.
83 citations,
December 2001 in “Journal of Investigative Dermatology” Minoxidil boosts hair growth by targeting adenosine and possibly sulfonylurea receptor 2B.
76 citations,
December 2018 in “Aesthetic Plastic Surgery” Platelet-rich plasma may help in skin and hair treatments, and with muscle and joint healing, but more research is needed to fully understand its benefits and limitations.
75 citations,
May 1986 in “Clinics in endocrinology and metabolism” Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.
73 citations,
August 2011 in “Stem Cell Research” Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.
72 citations,
December 2009 in “Organic and Biomolecular Chemistry” Mercuric triflate is an effective catalyst for various organic reactions, working well at room temperature with high yields.
71 citations,
January 2014 in “Journal of Proteome Research” Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.
67 citations,
January 2022 in “Theranostics” Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
65 citations,
November 2012 in “Tissue Engineering Part B-reviews” Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.