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Organotypic culture systems can grow skin tissues that mimic real skin functions and are useful for skin disease and hair growth research, but they don't fully replicate skin complexity.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Hair growth is influenced by various body and external factors, and neighboring hairs communicate to synchronize regeneration.

Distinct β-catenin patterns are linked to cell growth, not cell death, in lung cancer.

Different lab conditions and light treatment methods change how human skin cells respond to light therapy.

Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

Green tea compound EGCG helps mink hair follicles grow by affecting certain cell growth pathways.

Proactive monitoring and management are essential to maximize the benefits of Trastuzumab Deruxtecan while minimizing serious side effects.

Alopecia areata is an autoimmune condition causing hair loss, linked to genetic factors and immune system issues, with no cure yet.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Lactate production is important for activating hair growth stem cells.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

Hair grays due to oxidative stress and fewer functioning melanocytes.