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Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Hydroxypinacolone retinoate is a potent anti-aging ingredient for skin that is more effective and less irritating than other forms of retinoids.

The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.

Spin traps like PBN could protect skin from pollution and sunlight in cosmetics but need more research for safe use.

Oxidative stress is likely important in causing telogen effluvium, and antioxidants might help treat it.

Wild African goats have genetic adaptations for surviving harsh desert conditions.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Forsythiaside A helps reduce brain damage from lack of blood flow by activating certain protective pathways.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Researchers created a model to understand heart aging, highlighting the role of microRNAs and identifying key genes and pathways involved.

A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.

Nicotinic acid reduces excessive oil production in skin cells by activating a specific receptor, which could help treat acne.

Lifestyle choices like stress, smoking, heavy drinking, sun exposure, and chemical hair treatments might speed up hair loss in people with androgenetic alopecia.

Radiation therapy damages skin structure and immune function, causing inflammation and potential hair loss.

BMI1 is essential for preventing hair greying and maintaining hair color.

Epigenetic factors play a crucial role in skin health and disease.

Human foreskin does not show aging or reduced cell growth after radiation, and H2A.J is not a good marker for radiation-induced aging.

Removing Dicer from pigment cells in newborn mice causes early hair graying and changes in cell migration molecules.

Removing centrosomes from skin cells leads to thinner skin and stops hair growth, but does not greatly affect skin cell differentiation.

Rac1 is essential for proper hair structure and color.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.

New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.

Mitochondrial problems in tooth cells lead to bad enamel and dentin development in mice.

Fzd2 is important for skin and hair development through various signaling ways.

Oleoylethanolamide (OEA) safely boosts fat production in skin cells and may help treat dry skin and reduce inflammation.

Claudin-1 and Claudin-3 are crucial for keeping hair follicle structure and preventing a type of hair loss called telogen effluvium.

Older hair follicle stem cells have a reduced ability to renew themselves, leading to more hair loss.

The role of γδT-cells in causing alopecia areata remains unclear.