32 citations
,
June 1976 in “JAMA” In this study, nine individuals who underwent rigorous weight loss programs experienced significant hair loss, which researchers attributed to insufficient energy supply to the hair matrix, with regrowth occurring within months.
19 citations
,
April 2015 in “Developmental Dynamics” This study reports that dynamic interactions between stem cells and their niche, influenced by macro-environmental factors, regulate regenerative behavior in integument pattern formation.
June 1997 in “The American Journal of Cosmetic Surgery” This article discusses the use of scalp stretching techniques to enhance donor hair supply for hair restoration, but it reports no new clinical findings.
May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study reported the first comprehensive transcriptome atlas of the extraorbital lacrimal gland in mice, identifying over 41 cell subclasses and revealing significant cell-cell communication networks, particularly among innate lymphoid cells.
December 2021 in “INDIGO (University of Illinois at Chicago)” This study used single-cell RNA sequencing to characterize 19 distinct cell populations in sheep hair follicles, uncovering differentiation signatures and intercellular communication that may influence wool curvature and sheep breeding.
5 citations
,
March 2017 in “Molecular biology of the cell” This article summarizes discussions from a minisymposium on organelle contact sites, highlighting new insights into their roles in cellular processes, but reports no novel experimental results.
4 citations
,
September 2004 in “Experimental Dermatology” This review discusses the role of connexin mutations in various human disorders, highlighting their impact on ectodermal epithelial phenotypes like hearing loss and skin abnormalities, but it presents no new clinical findings.
18 citations
,
December 2024 in “Journal of Drugs in Dermatology” In this literature review, exosomes show promise in cosmetic dermatology for skin rejuvenation and hair restoration; however, challenges like inconsistent isolation methods and lack of FDA approval necessitate further clinical trials to ensure long-term safety and efficacy.
2 citations
,
February 2025 in “Advances in Cosmetic Surgery” Exosome therapies could help with skin and hair issues, but more testing is needed.
1 citations
,
January 2010 in “Journal of Bioscience and Bioengineering” This review explores recent studies on exosomes for hair loss treatment and reports no new clinical findings, highlighting their potential role as promising agents in hair regeneration.
34 citations
,
November 1991 in “Choice Reviews Online” This work reviews the structure and functions of the nervous system, covering topics from nerve cell properties to the mechanisms of learning and memory, but does not present new research findings.
3 citations
,
February 2023 in “International Journal of Molecular Sciences” This review discusses the composition, preparation, and applications of autologous platelet and extracellular vesicle-rich plasma, highlighting its potential benefits and the need for further research, but it reports no new clinical findings.
August 2026 in “International Journal of Nanomedicine” This review highlights the potential of exosome-based therapies for androgenetic alopecia by modulating key signaling pathways in hair follicles, suggesting a promising treatment option that requires further research to validate long-term safety and efficacy.
133 citations
,
September 2013 in “Nature Reviews Molecular Cell Biology” Different types of stem cells and their environments are key to skin repair and maintenance.
35 citations
,
May 2021 in “Nature communications” This study found that basement membrane components and structures in mouse hair follicles are highly specialized for specific inter-tissue interactions, with laminin α5 playing a crucial role in hair cycle regulation and anchoring.
610 citations
,
April 2014 in “Nature Reviews Immunology” This review discusses the complex mechanisms regulating skin immunity to balance host defense with inflammation, but reports no new findings.
53 citations
,
January 1993 in “Biochemical Pharmacology” This study reports a method for efficiently synthesizing chromeno-pyrimidine-N-oxides in good to excellent yields, confirmed by X-ray analysis, through a reaction between 4-chloro-3-formylcoumarin and aromatic carboximide oximes.
50 citations
,
July 2021 in “Nature Communications” This study found that the antiandrogen drug enzalutamide reduced TMPRSS2 levels and significantly decreased SARS-CoV-2 entry and infection in lung cells, supporting further clinical trials for COVID-19 treatment.
38 citations
,
July 2019 in “Nature Communications” This study found that Par3 plays a crucial role in maintaining epidermal homeostasis by regulating Rho/actomyosin contractility and ensuring mitotic accuracy, with potential implications for other self-renewing epithelia.
22 citations
,
February 2008 in “Biochemical and Biophysical Research Communications” Androgen effects on hair follicles vary by skin area.
116 citations
,
September 2020 in “Nature Communications” This study reports previously unrecognized cellular complexity in growing mouse incisors, suggesting species-specific differences in cell dynamics between mouse and human teeth related to growth and differentiation.
January 2025 in “Cell Communication and Signaling” This study reviews the role of the zinc finger protein CXXC5 in cellular signaling and its implications for cancer, discussing how its dysregulation is linked to various physiological and pathological processes, as well as potential therapies targeting CXXC5.
July 2026 in “Nature Communications” This study reports that brief exposure to low intensity and low frequency ultrasound was able to transiently break cellular microtubules and mitigate hair follicle damage, suggesting a potential method to prevent hair loss during chemotherapy with taxanes like paclitaxel.
The researchers observed that in cichlid fishes with different dental structures, tooth replacement accelerated more than three times following tooth extraction, alongside distinct changes in gene expression and cellular interactions over one week, providing insights into tooth regeneration mechanisms in vertebrates.
1160 citations
,
November 2018 in “Physiological Reviews” This review discusses the potential of single cell technologies to improve understanding and treatment of impaired wound healing and reports no new clinical results.
33 citations
,
January 2018 in “The International Journal of Developmental Biology” This review discusses the dual role of cellular senescence in ageing and tissue repair and suggests potential therapeutic applications, with no new experimental results reported.
18 citations
,
January 2013 in “International Society of Hair Restoration Surgery” This article discusses the importance of clinical biopreservation for cells and tissues in hair transplantation and regenerative medicine, reporting no new empirical findings.
15 citations
,
January 2020 in “ACS Applied Materials & Interfaces” This study reported that a novel chitosan/polyvinyl alcohol nanofiber sponge effectively enhances the hair follicle-inducing ability of dermal papilla multicellular spheroids in a mouse model.
11 citations
,
May 2010 in “Journal of the South African Veterinary Association” This case report describes how a treatment with mycophenolate mofetil and prednisone may be effective in managing autoimmune subepidermal blistering dermatosis in dogs while allowing for steroid reduction.
2 citations
,
December 2016 in “EMBO journal” This obituary honors Susan Lee Lindquist for her pioneering work in cellular protein folding and genetics, highlighting her significant contributions to science and mentorship in her nearly 40-year career.