Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study reported that newly developed minoxidil Pickering emulsion gels, designed using cellulose stabilizers, showed promising results for promoting hair regrowth and targeting hair follicles by enhancing the delivery and stabilization properties of the formulation in a hair loss treatment context.

This study found that both crude Spirulina extract and C-phycocyanin showed similar effects on keratinocyte proliferation and wound healing, with C-phycocyanin performing better in tissue regeneration in vivo on the 7th day.

In this study, researchers identified CENPV as a new CYLD interacting partner that localizes to primary cilia and regulates acetylated tubulin levels, offering insights into the pathogenesis of skin appendage tumors.

This industry report describes several new collaborations and licensing agreements in the field of regenerative medicine, focusing on stem cell technologies, and reports no new clinical results.

This study suggests that cyclosporine may directly affect epithelial cell growth, potentially leading to broader use of its nonimmunosuppressive analogues in treating hyperproliferative epidermal diseases.

This study found that Cepharanthine may mitigate doxorubicin-induced senescence by reducing SA-β-Gal activity and restoring autophagy in cell models, offering insights for antiaging drug development.

This study suggests that primary cilia may enhance the proliferation of skin-derived precursors when combined with lithium chloride and platelet-derived growth factor, potentially targeting them for stem cell-based therapies.

This article discusses junctional epidermolysis bullosa caused by COL17 deficiency, noting a lack of experimental therapies and the impact of nonsense mutations, but it reports no new clinical results.

In this study, the methanolic extract of Tridax procumbens Linn demonstrated significant antiulcer activity in a mice model of acetic acid-induced ulcerative colitis, offering 57.12% ulcer protection compared to 50.60% by the standard drug prednisolone.

In this study, the ethyl acetate extract of Semecarpus anacardium Linn leaves was reported to induce cytotoxicity in cancer cells, cause cell cycle arrest, and suppress tumor growth in mice.

In this laboratory study, the researchers found that combining dermal papilla cell-derived exosomes with collagenous sequences significantly enhanced hair follicle stem cell migration and proliferation, highlighting a potential strategy for hair regeneration through modulation of the hsa-novel-238a-CASP9 axis.

This study found that a newly developed injectable hydrogel combined with human umbilical cord-mesenchymal stem cells significantly accelerated wound healing and reduced inflammation in full-thickness cutaneous wounds.

This study found that L-cystine, D-pantothenat, and miliacin can enhance the metabolic capacity and proliferation of human keratinocytes, with a combination of these additives potentially providing synergistic benefits in growth media.

In this study, researchers found that inhibiting IKKα in patient-derived CCS tumour models reduces tumour viability, supporting the potential for topical IKKα inhibitors as a treatment for CCS.

A rare skin reaction from cancer treatment was successfully managed with topical treatments and antihistamines.

This study identified 8-hydroxy germacrene B from Curcuma aeruginosa as a highly potent in-vitro 5-alpha reductase inhibitor with significant anti-androgenic activity, while exhibiting mild cytotoxicity on prostate cancer cells without affecting human dermal papilla cells at tested concentrations.

In diabetic mice, this study reported that the multifunctional hydrogel CPGel achieved complete wound closure in 21 days, showing promise in improving chronic wound healing through antibacterial, antioxidative, and tissue regeneration properties.

This study found that the curl in hair is due to the arrangement of different cell types, with shorter paracortical cells inside the curve and longer orthocortical cells outside.

In this study, researchers found that supplementation with L-cystine, either alone or with a keratin hydrolysate, significantly improved hair density, hair and nail brightness, and nail growth in women experiencing acute telogen effluvium and brittle nail syndrome over three months.

This study found that the PPARγ modulator NAC-GED-0507-Levo may protect hair follicles from chemotherapy-induced damage, potentially offering a strategy to address irreversible hair loss in cancer patients.

This study found that curcumin encapsulated in liposomes enhanced photodynamic therapy's effectiveness against skin cancer cells while reducing toxicity to normal human keratinocytes.

This study found that the natural extract e-CAF promotes the proliferation and migration of human hair dermal papilla cells in vitro, suggesting potential benefits for skin regeneration and tissue repair.

This article reviews autologous cell therapy for facial wrinkles, detailing the use of LaViv and its adverse events, but reports no new clinical results.

Ceramide may help delay hair aging by restoring stressed hair cells.

In this study, researchers formulated a nanosuspension of kenikir leaf extract that meets physical criteria and exhibits cytotoxic activity against MCF-7 breast cancer cells.

Telitacicept effectively improved hair regrowth in a woman with lupus and alopecia.

This study found that bulge keratinocytes in mice develop resistance to glucocorticoid treatment more slowly than interfollicular keratinocytes and do not significantly aid in repairing glucocorticoid-induced skin atrophy within five days.

The authors report that a 62-year-old woman with invasive conjunctival squamous cell carcinoma experienced complete remission two years after combining cemiplimab, retinoic acid, and IFNα-2b treatments, highlighting potential utility despite limited availability of IFNα-2b.

This study found that curcumin spanlastics demonstrated greater antimicrobial, antioxidant, and anticancer activities in the MCF-7 breast cancer cell line compared to curcumin alone or curcumin nanocrystals, also affecting several cancer-related protein markers and showing enhanced solubility and activity.

This review examines various treatments for dissecting cellulitis, noting isotretinoin may offer the best chance for remission despite limited long-term data and calls for more clinical studies.