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This study used integrated single-cell chromatin and transcriptomic analyses in developing mouse skin to uncover gene networks involved in skin lineage specification and identified Mef2c+ upper fibroblasts as potential precursors to certain muscle-like structures, with cross-species findings in human skin.

This study suggests that the secretome from amniotic fluid-derived mesenchymal stem cells overexpressing Nanog could stimulate hair growth and increase follicle density, potentially aiding in alopecia treatment.

Injecting lentiviral vectors into early gestation mice effectively targets skin stem cells for potential gene therapy.

In this research, authors found that skin-resident ILCs regulate sebaceous gland function and microbial balance, emphasizing an immune-epithelia system that supports host-microbe symbiosis.

This review discusses the roles of KIT and mast cells in skin physiology and pathology using different genetic models and reports no new clinical results; the authors suggest further exploration of KIT deficiency.

This study found that an extract from the root of Sophora flavescens Aiton significantly improved hair growth in patients with androgenetic alopecia over 6 months.

This article describes a method using the CUBIC protocol to clarify and visualize molecular and cellular interactions in mouse skin biopsies at single cell resolution, but does not provide new biological findings.

This review provides a comprehensive guide to serum-free human hair follicle organ culture methods, highlighting research opportunities, standardization efforts, and potential applications without reporting new empirical findings.

This study reports that C3H/HeJ mice and DEBR rats serve as effective models for screening potential treatments for human alopecia areata, despite certain challenges in predictability and cost.

The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.

This study reveals that CSPG4-positive basal cell keratinocytes show distinct global gene expression from CSPG4-negative cells, despite similar colony-forming efficiency.

This review discusses how regulatory T cells, known for their immunosuppressive role, also produce repair mediators critical for tissue repair and regeneration, acting on non-immune cells in tissue-specific contexts, and highlights areas for future research in tissue repair, fibrosis, and cancer.

This review highlights the role of reactive oxygen species in root hair growth and cell expansion in plants but does not report new empirical findings.

This study found that PDCD4 protein expression is reduced in various skin cancers compared to normal skin, suggesting its potential role in preventing or treating certain skin cancers.

This review discusses the role of cholesterol homeostasis in hair follicle biology and its potential connections to various hair disorders, but it reports no new findings.

This review discusses recent advancements in generating appendage-bearing skin organoids from pluripotent stem cells and their potential applications in dermatological research, but reports no new clinical results.

In this study, SIRT1-modified human umbilical cord mesenchymal stem cells reduced peritoneal fibrosis in a rodent model, suggesting potential as a treatment strategy for peritoneal dialysis-induced damage.

In this study, researchers successfully generated functional and long-lived melanocytes from human embryonic stem cells, demonstrating their biocompatibility and high engraftability in mice, which may aid in developing treatments for pigmentary skin disorders.

This review discusses immune privilege in anagen hair follicles and its collapse in alopecia areata, emphasizing the importance of restoring this function for effective management and disease relapse prevention.

This study describes a method for isolating stem cells and keratinocytes from mouse hair follicles using FACS technology, facilitating the study of stem cell biology.

In mouse models of alopecia areata, this study found increased dilation of lymphatic vessels in affected mice, with associated changes in gene expression related to vascular growth and immune cell movement.

This study reviews the regenerative potential and clinical applications of exosomes derived from mesenchymal stem cells in conditions like COVID-19, alopecia, skin aging, and osteoarthritis, highlighting their role as a promising tool in regenerative medicine.

This review discusses the paracrine properties of cardiac stem cells and pericytes in regenerative medicine for ischaemic diseases and reports no new clinical results.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

This study suggests that exosomes derived from dermal papilla cells, especially those cultured in three dimensions, promote hair growth and regeneration by enhancing follicular cell activity.

The researchers reported that in hairless mice, epidermal cell division orientations and epidermal thickness varied by body site, with dorsal and ear epidermis primarily dividing parallel to the basement membrane, unlike hind paw and tail epidermis.

This study found that exosomes from hair follicle mesenchymal stem cells overexpressing lncRNA H19 promoted diabetic skin wound healing by enhancing cell proliferation, migration, and reducing pyroptosis.

Stem cell research and regenerative medicine have made significant advancements in treating various diseases and conditions.

This Ph.D. project aims to evaluate the self-assembling potential of hair keratin extracts and study the cellular response to both crude and purified keratins, highlighting their potential applications from biomedical to water remediation.

This review outlines the current state and future prospects of using layer-by-layer self-assembly for cell encapsulation in biomedical applications, such as cell-based biosensors, transplantation, and tissue engineering, while also discussing its limitations and potential advancements.